Not really apropos, but interesting (to me, anyway).  Someone (I forgot who; 
I'm sorry) said once that "the entire history of medicine before 1900 is a 
history of the placebo effect."  I think it's a bit of an exaggeration, but 
just a bit.

m


--
Marc Carter, PhD
Associate Professor and Chair
Department of Psychology
College of Arts & Sciences
Baker University
--




________________________________

        From: Frantz, Sue [mailto:sfra...@highline.edu]
        Sent: Tuesday, August 25, 2009 12:22 PM
        To: Teaching in the Psychological Sciences (TIPS)
        Subject: [tips] Placebos getting stronger?




        Through the Improbable Research blog comes this article from Wired, 
"Placebos Are Getting More Effective. Drugmakers Are Desperate to Know Why."  
http://www.wired.com/medtech/drugs/magazine/17-09/ff_placebo_effect?currentPage=all



        An excerpt:

        Some products that have been on the market for decades, like Prozac, 
are faltering in more recent follow-up tests. In many cases, these are the 
compounds that, in the late '90s, made Big Pharma more profitable than Big Oil. 
But if these same drugs were vetted now, the FDA might not approve some of 
them. Two comprehensive analyses of antidepressant trials have uncovered a 
dramatic increase in placebo response since the 1980s. One estimated that the 
so-called effect size (a measure of statistical significance) in placebo groups 
had nearly doubled over that time.

        It's not that the old meds are getting weaker, drug developers say. 
It's as if the placebo effect is somehow getting stronger.

        Additionally the article provides a nice history and overview of the 
modern placebo effect as well as some current applications, such as this 
(ethically suspect) one.



        One recent afternoon in [Fabrizio Benedetti's] lab [at the University 
of Turin], a young soccer player grimaced with exertion while doing leg curls 
on a weight machine. Benedetti and his colleagues were exploring the potential 
of using Pavlovian conditioning to give athletes a competitive edge 
undetectable by anti-doping authorities. A player would receive doses of a 
performance-enhancing drug for weeks and then a jolt of placebo just before 
competition.





        --
        Sue Frantz <http://flightline.highline.edu/sfrantz/>                    
                      Highline Community College
        Psychology, Coordinator                Des Moines, WA
        206.878.3710 x3404                      sfra...@highline.edu 
<mailto:sfra...@highline.edu>

        Office of Teaching Resources in Psychology, Associate Director

        Project Syllabus <http://teachpsych.org/otrp/syllabi/syllabi.php>

        APA Division 2: Society for the Teaching of Psychology 
<http://teachpsych.org/otrp/syllabi/syllabi.php>



        APA's p...@cc Committee <http://www.apa.org/ed/pcue/ptatcchome.html>






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        Bill Southerly (bsouthe...@frostburg.edu)



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