On 23 Mar 2010 at 7:22, Lilienfeld, Scott O wrote:

>  I'm definitely no expert on this one, but my distinct impression is that 
> it's far too early to call 
> "use it or lose it" a myth. The famous "nun study" and several other 
> longitudinal studies point to 
> possible benefits of "cognitive exercise" and mental activity as protective 
> factors against 
> dementing illness, although my understanding is that the causal direction 
> here is still somewhat 
> controversial (people with better cognitive reserves to start with may be 
> more likely to engage in 
> cognitive exercise). Attempts to control for potential covariates still point 
> to possible causal 
> effects of cognitive exercise, but I'm not sure the issue is resolved 
> conclusively.

My impression is similar to that of Scott's, that there is some 
evidence that mental activity (doing crossword puzzles, say), is 
protective of cognitive function in the elderly. But I also agree 
that the main problem is in deciding whether it's more a case of 
"those who can, do" rather than "use it or lose it". One of the 
earliest signs of dementia may be an inability to carry out 
cognitive exercises and a corresponding lack of interest in them. 
Rather than a cause of dementia, it may be an early result. 

My mother, for example, was an avid devotee of crossword 
puzzles, and I used to clip them out from the newspaper and 
enlarge them on a photocopier for her poor vision.  But I knew 
something was up when she started leaving them undone. 

The best evidence, I believe, for a  protective effect against 
cognitive decline is not mental activity, but physical.  For 
example, a recent Cochrane review (Angevaren et al, 2008) of 
randomized controlled trials cautiously concludes:

"There is evidence that aerobic physical activities which improve 
cardiorespiratory fitness are beneficial for cognitive function in 
healthy older adults, with effects observed for motor function, 
cognitive speed, delayed memory functions and auditory and 
visual attention. However, the majority of comparisons yielded 
no significant results".

Me, I'm getting regular doses of skiing and tennis just in case. 
Well no, actually, because they're fun. But it would be ok if they 
helped as well. Now, where did I leave my car keys?

Stephen

Cochrane Database Syst Rev. 2008 Apr 16;(2):CD005381.
Physical activity and enhanced fitness to improve cognitive function in older 
people without known cognitive impairment.

Angevaren M, Aufdemkampe G, Verhaar HJ, Aleman A, Vanhees L.


--------------------------------------------
Stephen L. Black, Ph.D.          
Professor of Psychology, Emeritus   
Bishop's University               
e-mail:  sblack at ubishops.ca
2600 College St.
Sherbrooke QC  J1M 1Z7
Canada
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