Don't they do sequential statistical analysis on such large scale studies? That 
is, aren't they obligated by ethics to analyze the data every few months and if 
unambiguous evidence of efficacy is developed immediately switch all control 
participants to the effective treatment?

Paul C Bernhardt
Frostburg State University
Frostburg, MD, USA
pcbernhardt[at]frostburg[d0t]edu



On Oct 2, 2010, at 3:05 PM, Joan Warmbold wrote:

> http://www.nytimes.com/2010/09/19/health/research/19trial.html?pagewanted=1&_r=1&emc=eta1
> 
> When does random assignment of subjects to groups receiving different 
> treatments for cancer become unethical and inhumane?  This article in the 
> NYT's certainly provokes such consideration.
> 
> Joan
> Joan Warmbold Boggs
> [email protected]
> 
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