I recently received a couple questions about the effect of SSRIs on depression 
and I'm not quite sure of the answer.  Would anyone care to edify us on these 
questions?

Do people with depression produce enough serotonin, but it just isn’t getting 
absorbed? In other words, it gets released and then just hangs out in the 
synapse area? Or do they not produce enough serotonin to begin with and what 
doesn’t get absorbed creates a “deficiency”?
As I understand it, SSRIs prevent serotonin from going back into the 
originating neuron and MAOs destroy the serotonin left in the synapse and that 
medication stops this destruction from happening. Both of these are designed to 
keep the serotonin levels high. Why not just increase the amount of serotonin 
in the body say with 5-HTP supplement?  Would more serotonin in the synapse 
allow more to be absorbed?

Michael

Michael A. Britt, Ph.D.
[email protected]
http://www.ThePsychFiles.com
Twitter: mbritt






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