No problems here solid as a rock for me. In fact I'd recommend everyone to
upgrade to this version. The browsing experience is better with a greatly
improved Gnash plugin.
I had a problem with a different system to the one I'm currently using. It
was to do with the desktop panels and icons disappearing (issue described in
post above).
For this reason I'd suggest trying Trisquel 5 using the Live CD/USB first,
then doing a full install by whether method you prefer. I'm suggesting this
because the issues I had also showed up in Live CD mode.