I made it a little better.
Since the Trisquel theme clashes with Guix apps' Adwaita, I changed
everything to Adwaita.
Since Adwaita icons and panel color clashes with the default wallpaper, I
changed the wallpaper to the Trisquel 6 wallpaper.
Since a thick, solid panel is ugly, I resized it from 44 pixels to 30 pixels.
I would have kept the same thickness and made it transparent, but changing
the transparency leaves patches of solid black underneath applets, and
https://www.howtogeek.com/howto/43673/how-to-make-the-gnome-panels-in-ubuntu-totally-transparent/
could not help me fix it.
I still don't think it's as nice as Trisquel's defaults, though, and Qt apps
are stil ugly.