Some inputs for what it's worth... with a self built 4.10.4 from a few
weeks back but same config as yours (AMD pinctrl disabled) - no other
changes:

- USB works fine on all the ports I tried (several devices)
- Network works fine (both ports Intel and Killer Networks)
- NVMe drive works fine
- SATA drive works fine
- NVidia closed source drivers work fine with the patch (see above in this 
thread for pointers to make the nvidia driver work on 4.10.x)

- I haven't tested audio but it's displayed correctly in the settings

I haven't yet noticed something that doesn't work because of that
change.

I'm tempted to think that the gpio ports are possibly used to control
the onboard LED lighting and stuff like that...

Board is GA-AX370-Gaming5

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https://bugs.launchpad.net/bugs/1671360

Title:
  System doesn't boot properly on Gigabyte AM4 motherboards (AMD Ryzen)

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