All GTK programs are broken. Same message: 
xxxxx@warp:~$ export LANG="ru_RU.UTF-8"; leafpad
(leafpad:18666): dbind-WARNING **: 23:43:20.266: Couldn't register with 
accessibility bus: Did not receive a reply. Possible causes include: the remote 
application did not send a reply, the message bus security policy blocked the 
reply, the reply timeout expired, or the network connection was broken.

Geany, Leafpad, Gedit and Opera save file dialogs don't allow Russian language 
input. Qt programs works fine. Launching with sudo fix problem:
xxxxx@warp:~$ sudo leafpad
(leafpad:28016): GLib-GIO-CRITICAL **: 00:27:57.489: g_dbus_proxy_new: 
assertion 'G_IS_DBUS_CONNECTION (connection)' failed 

Dbus is running. 
xxxxx@warp:~$ echo $DBUS_SESSION_BUS_ADDRESS
unix:path=/run/user/1000/bus
xxxxx@warp:~$ echo $DBUS_SESSION_BUS_PID

(empty string)
========================
This happen after upgrade from 16.04.6 to 18.04.5 . Kernel 5.4.0-42-generic. I 
have old kernels and can test with it. PC on MSI P67S motherboard, no suspends, 
just XscreenSaver.

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https://bugs.launchpad.net/bugs/1222356

Title:
  WARNING: Couldn't register with accessibility bus: Did not receive a
  reply.

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