Oui, selon cet article la fr�quence serait de 40 � 50%...

Systematic Lung Scans Reveal a High Frequency of Silent Pulmonary
Embolism in Patients With Proximal Deep Venous Thrombosis  
 
 
  Michel Meignan, MD; Jean Rosso, MD; H�l�ne Gauthier, MD; Fran�oise
Brunengo, MD; Sophie Claudel, PhD; Luc Sagnard, MD; Pascal d'Azemar, MD;
G�rald Simonneau, MD; Bernard Charbonnier, MD 


Background  A high frequency of asymptomatic pulmonary embolism (PE) has
been reported in patients with deep venous thrombosis (DVT) in studies
of a limited number of patients using varying criteria for lung scan
assessment.

Objectives  To estimate the frequency of PE using systematic lung scans
in a large group of outpatients with DVT and to compare the results
using varying lung scan assessment criteria.

Methods  An international multicenter study comparing 2 different
regimens of low-molecular-weight heparin nadroparin in DVT: perfusion
lung scans were performed in 622 outpatients with no clinical indication
of PE and with proximal DVT confirmed by venography. Three hundred
seventy-nine of these patients underwent ventilation lung scans.
High-probability (HP) scans for PE were assessed separately using either
ventilation scans or chest radiographs to define mismatched perfusion
defects.

Results  Perfusion scans showed abnormalities in 82% of the patients;
59% had segmental defects and 30% had normal scans or scans with a very
low probability of PE. Depending on the criteria used, 32% to 45% had HP
scans for PE; these percentages were higher in young patients. No
relationship was found between extent of thrombosis and HP scans. The
estimated frequency of silent PE was 39.5% to 49.5%. During a 3-month
follow-up period during which the patients received therapy, the rate of
PE recurrence was low (1.3%) and did not differ between patients with
baseline HP scans and those with normal scans.

Conclusions  Regardless of what interpretative criteria are used for
assessing lung scans in PE, the frequency of silent PE is 40% to 50% in
patients with DVT. A baseline lung scan may easily detect PE in these
patients but is not useful for predicting early thromboembolic
recurrences that may occur during therapy.

Arch Intern Med. 2000;160:159-164



Jean Levasseur
CHRDL, Joliette

-----Message d'origine-----
De�: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] De la part de Martin
Chenier
Envoy�: 12 mars, 2003 09:09
��: URG-L Mailing List
Objet�: URG-L: [Pas de sujet]

Faut dire �galement qu'on trouverait chez la plupart des patients avec
une TPP 
proximale des embolies pulmonaires si l'investigation �tait pouss�e �
fond. 
Je te r�f�re au texte du consensus � ce sujet.

MC



Tu as �crit:



> Tu as �crit:
> > Une "derni�re" toute petite question sur les TPP.Traitez-vous en
externe
> > imm�diatement(i.e. d�s que le Dx est pos� avec certitude)toutes les
TPP
> > du MI � savoir aussi proximales soient-elles? Et si le doppler parle
de
> > "thrombus flottant",en externe aussi? Je sais que le Tx est le
m�me,je
> > sais aussi que thrombus flottant ou pas,embolie pulmonaire ou pas,le
Tx
> > est le m�me...mais j'ai une esp�ce de blocage � donner cong� � ces
> > patients imm�diatement apr�s le Dx et le d�but de l'HBPM.
> >
> > C.
>
> -Il existe des crit�res pour traiter en externe. Tu trouveras un
r�sum� des
> crit�res � l'adresse suivante :
>
>  http://www.chestnet.org/guidelines/antithrombotic/p9.php
>
> -
> Martin Ch�nier
>
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-- 
Martin Ch�nier

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