URG-L: tramadol

Mon, 10 Sep 2007 17:48:07 -0700 

Moins bon que l'oxycodone
 
Unique Identifier       9701294
        
Authors Turturro
<http://gateway.tx.ovid.com/gw2/ovidweb.cgi?S=KGJNFPNBEFDDKBDKNCJLFFJLONPPAA
00&Search+Link=%22Turturro+MA%22.au.> MA. Paris
<http://gateway.tx.ovid.com/gw2/ovidweb.cgi?S=KGJNFPNBEFDDKBDKNCJLFFJLONPPAA
00&Search+Link=%22Paris+PM%22.au.> PM. Larkin
<http://gateway.tx.ovid.com/gw2/ovidweb.cgi?S=KGJNFPNBEFDDKBDKNCJLFFJLONPPAA
00&Search+Link=%22Larkin+GL%22.au.> GL.
        
Authors Full Name       Turturro, M A. Paris, P M. Larkin, G L.
        
Institution     Department of Emergency Medicine, The Mercy Hospital of
Pittsburgh, PA, USA. [EMAIL PROTECTED]
        
Title   Tramadol versus hydrocodone-acetaminophen in acute musculoskeletal
pain: a randomized, double-blind clinical trial.
        
Source  Annals of Emergency Medicine. 32(2):139-43, 1998 Aug.
        
Abstract        STUDY OBJECTIVE: To evaluate the efficacy of an oral
tramadol preparation versus that of an oral hydrocodone-acetaminophen
preparation in acute musculoskeletal pain. METHODS: A randomized,
prospective, double-blind clinical trial was conducted in an urban teaching
emergency department with an annual census of 41,000. Participants comprised
a convenience sample of 68 adult ED patients with acute musculoskeletal pain
caused by minor trauma. Thirty-three patients received tramadol (100 mg),
and 35 patients received hydrocodone-acetaminophen (5 mg hydrocodone with
500 mg acetaminophen). The drugs were prepared in identical-appearing
capsules. Pain was evaluated by a 100-mm visual analog scale (VAS) at
baseline and at 30, 60, 90, 120, and 180 minutes after dosing. VAS scores
were analyzed by 2-way repeated-measures ANOVA, and nominal data were
analyzed by Fisher's exact test. RESULTS: Mean pain scores did not differ at
baseline (tramadol, 68.3+/-21.8; hydrocodone-acetaminophen, 69.1+/-17.8;
P=NS) but were significantly lower in the hydrocodone-acetaminophen group
beginning at 30 minutes through 180 minutes. There were 6 dropouts as a
result of reported inadequate analgesia, 3 in each group (P=NS). The
discharge diagnoses and prevalence of side effects did not differ
significantly between groups. CONCLUSION: Tramadol provides inferior
analgesia to hydrocodone-acetaminophen in ED patients with acute
musculoskeletal pain.
        
Publication Type        Clinical Trial. Journal Article. Randomized
Controlled Trial. Research Support, Non-U.S. Gov't.     

  _____  

From: [email protected] [mailto:[EMAIL PROTECTED] On Behalf Of Catherine
Bich
Sent: 10 septembre 2007 18:40
To: [email protected]
Subject: URG-L: tramadol



Bonjour,

 

Utilisez-vous régulièrement le tramadol,seul ou en association avec
l’acetaminophen(tramacet)?

 

L’utilisez-vous grosso modo en remplacement de l’empracet ou utilisez-vous
l’un et l’autre ?

 

Qu’est-ce qui vous amène à Rx l’un ou l’autre ou l’un et l’autre ?

 

Le coût est-il comparable ?

 

Est-ce maintenant pour vous l’analgésique de moyenne puissance le plus
fréquemment prescrit pour la foule de conditions moyennement douloureuses
qui est notre bread and butter à l’urgence ?

 

Merci de vos commentaires.

 

C.

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