J'ai la meme impression que Julie

On Tue, Sep 2, 2008 at 1:02 PM, Julie Boyer <[EMAIL PROTECTED]> wrote:

>  En effet, c'est surprenant.
>
> Les patients qui tolèrent sont tellement plus relax, plus rapidement avec
> le BiPap. En plus, la majorité tolère bien. J'ai toujours eu l'impression
> que le Bipap prévenait l'intubation…. Peut-être que l'on traite le docteur
> ??? Les patients ont l'air mieux.
>
> Julie
>
>
>
> *From:* Alain Vadeboncoeur [mailto:[EMAIL PROTECTED]
> *Sent:* Tuesday, September 02, 2008 10:01 AM
> *To:* [EMAIL PROTECTED]
> *Subject:* URG-L: FW: InfoPOEM: CPAP and NIPPV no better than O2 in acute
> pulmonary edema (3CPO)
>
>
>
> FAscinant quand même!
>
>
>
> ALain
>
>
>  ------------------------------
>
> *From:* [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] *On Behalf Of *"Équipe
> éditoriale de amc.ca"
> *Sent:* 2 septembre 2008 05:21
> *To:* [EMAIL PROTECTED]
> *Subject:* InfoPOEM: CPAP and NIPPV no better than O2 in acute pulmonary
> edema (3CPO)
>
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>   *CPAP and NIPPV no better than O2 in acute pulmonary edema (3CPO)*
>
> *Clinical question *
> Does noninvasive ventilation improve outcomes in patients with acute
> cardiogenic pulmonary edema?
>
> *Bottom line *
> In patients with acute cardiogenic pulmonary edema, continuous positive
> airway pressure (CPAP) and noninvasive positive pressure support (NIPPV) do
> not reduce mortality or the risk of requiring intubation more than standard
> oxygen therapy. They may provide a small benefit in terms of greater relief
> of dyspnea. (LOE = 1b) <http://mailer.cma.ca/t/3129055/234493/102001/0/>
>
> *Reference *
> Gray A, Goodacre S, Newby DE, et al, for the 3CPO Trialists. Noninvasive
> ventilation in acute cardiogenic pulmonary edema. N Engl J Med
> 2008;359(2):142-151. <http://mailer.cma.ca/t/3129055/234493/822001/0/>
>
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> Randomized controlled trial (nonblinded)
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> *Synopsis *
> The optimal approach to noninvasive ventilation for patients with acute
> cardiogenic pulmonary edema remains unclear, with only a few small
> randomized controlled trials. CPAP provides the same level of positive
> airway pressure throughout the respiratory cycle, while NIPPV increases
> pressure more during inspiration than during expiration. There are
> theoretical reasons to think that NIPPV may be better, but it has also been
> associated with a greater risk of acute myocardial infarction. In this
> study, 1069 adults with acute cardiogenic pulmonary edema at 26 United
> Kingdom emergency departments were randomized to receive oxygen therapy,
> CPAP, or NIPPV. All patients had pulmonary edema on chest x-ray, a pH of
> less than 7.35, and a respiratory rate greater than 20 breaths per minute.
> Their mean age was 78 years and 57% were women. All patients received the
> assigned treatment for at least 2 hours, with the duration of further
> treatment determined by the treating physician. Groups were balanced at the
> start of the study and analysis was by intention to treat. Overall adherence
> to the assigned treatment was good, although patients initially assigned to
> oxygen were more likely to change therapy because of respiratory distress
> (8.4% vs 1.4% for CPAP and 3.4% for NIPPV; P < .001), while those assigned
> to NIPPV were more likely to change therapy because of patient discomfort
> (8.4% vs 5.2% for CPAP and 0.3% for oxygen; P < .001). After 7 days, there
> was no significant difference between groups regarding rates of mortality or
> need for intubation, or regarding mortality at 30 days. Patients receiving
> CPAP or NIPPV had a greater improvement on a 10-point dyspnea score than
> those receiving oxygen alone (4.6 vs 3.9 points), but this difference is of
> questionable clinical significance. There were also greater improvements in
> arterial pCO2 and pH, but again the clinical significance is uncertain.
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