> Kernel: 2.6.18-4-686

Try upgrading to 2.6.20. I've read about some issues with file handlers with 
2.6.18. After upgradiong I reduced iowait% significantly.

> Apache: 2.2.3-4
> MySQL: 5.0.32-Debian_7etch1-log

And did you make any diagnosis about mysql tuning? Like threads cache, queries 
cache slow queries etc? I gained a lot by that.


> mpstat:
> 
> 12:01:15     CPU   %user   %nice    %sys %iowait    %irq   %soft  %steal 
>   %idle    intr/s
> 12:01:15     all    2,43    0,02    0,51    9,98    0,12    0,01    0,00 
>   86,93    283,67
> 
> uptime:
> 
>  12:01:18 up 25 days,  2:22,  1 user,  load average: 2.67, 5.46, 6.00

And how comes that you got high load while 85% idling without any iowaits? Try 
observig this with top. It will show both load and CPU's usage same time.

Solt
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