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Date :  Fri, 24 Jun 2011 09:48:20 +0100
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--- Begin Message ---
Hi,

I am not sure whether there is a mailing list to share my (lack of) experience! However, I am contacting you because I found the following issue with queries for Entrez Gene IDs. Actually, initially, this was using biomaRt Bioconductor package but it is clearly not an issue of biomaRt. When I interrogate ENTREZ, duplicated items are returned: one with the correct Entrez ID, the others empty.

For example:
Input:
ENSMUSG00000026073
ENSMUSG00000026180
ENSMUSG00000053846
ENSMUSG00000035208
ENSMUSG00000069830
ENSMUSG00000078853
ENSMUSG00000020826
ENSMUSG00000030077
ENSMUSG00000050075
ENSMUSG00000070501

Normal output:

Ensembl Gene ID Associated Gene Name    MGI symbol      Chromosome Name Gene 
Start (bp) Gene End (bp)
ENSMUSG00000020826      Nos2    Nos2    11      78734289        78773756
ENSMUSG00000026073      Il1r2   Il1r2   1       40141613        40182064
ENSMUSG00000026180      Cxcr2   Cxcr2   1       74200563        74207812
ENSMUSG00000030077      Chl1    Chl1    6       103460870       103699671
ENSMUSG00000035208      Slfn8   Slfn8   11      82815660        82834312
ENSMUSG00000050075      Gpr171  Gpr171  3       58900370        58905743
ENSMUSG00000053846      Lipg    Lipg    18      75098976        75120917
ENSMUSG00000069830      Nlrp1a  Nlrp1a  11      70904699        70958290
ENSMUSG00000070501      BC094916        BC094916        1       175449848       
175466088
ENSMUSG00000078853      Igtp    Igtp    11      58013058        58021093

Output with Entrez Gene ID:

Ensembl Gene ID Associated Gene Name    MGI symbol      Chromosome Name Gene 
Start (bp) Gene End (bp)   EntrezGene ID
ENSMUSG00000020826      Nos2    Nos2    11      78734289        78773756        
18126
ENSMUSG00000026073      Il1r2   Il1r2   1       40141613        40182064        
16178
ENSMUSG00000026073      Il1r2   Il1r2   1       40141613        40182064        
ENSMUSG00000026180      Cxcr2   Cxcr2   1       74200563        74207812        
12765
ENSMUSG00000026180      Cxcr2   Cxcr2   1       74200563        74207812        
12765
ENSMUSG00000030077      Chl1    Chl1    6       103460870       103699671       
ENSMUSG00000030077      Chl1    Chl1    6       103460870       103699671       
12661
ENSMUSG00000030077      Chl1    Chl1    6       103460870       103699671       
ENSMUSG00000035208      Slfn8   Slfn8   11      82815660        82834312        
276950
ENSMUSG00000035208      Slfn8   Slfn8   11      82815660        82834312        
100505399

Ten items, but only 5 distinct,  are returned. So we are missing 5 items.
Of course the issue might be at the level of ENTREZ.
In anticipation, I thank you for your help.
Kind regards

Dr Henri-Jean Garchon

Henri-Jean Garchon, MD, PhD
Director of Research
Cochin Institute and Inserm U1016
Department of Immunology
Laboratory of Chronic Inflammation
Pavillon Hardy A 1st floor
27 rue du Faubourg Saint-Jacques
75014 Paris
France
phone +33 1 40 51 66 06
fax:+33 1 40 51 66 41
mail: [email protected]


--- End Message ---
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