Hi Heather,

This functionality is "correct". So if the filter is hidden in the federated 
source's config, even if you turn it on locally, you will not be able to see 
the filter. the only way to get around this is to import the data to a local 
database and then turn the filter you want on for all datasets using the mysql 
connection rather than the URL connection as you have currently.

Otherwise, the other option is to ask the consortium if they don't mind to have 
the filter unhidden.

hope this helps,
Marie


From: "Estrella, Heather" 
<[email protected]<mailto:[email protected]>>
Date: Wed, 29 Jun 2011 12:34:37 -0400
To: "[email protected]<mailto:[email protected]>" 
<[email protected]<mailto:[email protected]>>
Subject: [BioMart Users] Adding tumour sample ID to somatic mutation quick 
search in ICGC


Hi,

I’m trying to add a tumour_sample_id to both the somatic mutation and CNV quick 
searches in our local ICGC-formatted biomart. The queries work OK for local 
datasets, but not for any of the datasets that are federated in from 
dcc.icgc.org.  The queries filtered on 
“snp__simple_somatic_mutation__dm__tumour_sample_id” also work OK for advanced 
queries on both federated ICGC datasets and internal datasets.

Again, technically this should work fine as can be seen in the advanced 
queries, but for some reason, adding the filter to the quick search doesn’t 
work for federated queries. I’ve even compared the configs for the advanced 
tumour_sample_id filter (that works) and what I have in the quick search and 
they are the same.

I only get the error when adding the filter to the quick search that it is not 
working. Here’s the error message it returns:

2011-06-29 09:14:22,923 DEBUG [pool-1-thread-2:Log.java:143]: SENDING 
INSECURE(non-OAUTH) request

text

org.biomart.common.exceptions.BioMartException: HTTP Error 400 - Filter 
snp__simple_somatic_mutation__dm__tumour_sample_id not found in Breast Cancer 
(JHU, US)

        at 
org.biomart.queryEngine.SubQuery.executeMartServiceQuery(SubQuery.java:814)

        at org.biomart.queryEngine.SubQuery.executeQuery(SubQuery.java:726)

        at 
org.biomart.queryEngine.QueryRunnerThread.recurseSubQueries(QueryRunnerThread.java:171)

        at 
org.biomart.queryEngine.QueryRunnerThread.call(QueryRunnerThread.java:73)

        at 
org.biomart.queryEngine.QueryRunnerThread.call(QueryRunnerThread.java:37)

        at java.util.concurrent.FutureTask$Sync.innerRun(FutureTask.java:334)

        at java.util.concurrent.FutureTask.run(FutureTask.java:166)

        at 
java.util.concurrent.Executors$RunnableAdapter.call(Executors.java:471)

        at java.util.concurrent.FutureTask$Sync.innerRun(FutureTask.java:334)

        at java.util.concurrent.FutureTask.run(FutureTask.java:166)

        at 
java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1110)

        at 
java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:603)

        at java.lang.Thread.run(Thread.java:636)

2011-06-29 09:14:23,442 INFO  [1943435117@qtp-881305036-8:Log.java:165]: Total 
query time is 520 ms

2011-06-29 09:16:13,319 INFO  [689021860@qtp-881305036-4:Log.java:165]: 
Incoming XML query: <!DOCTYPE Query><Query client="webbrowser" processor="TSV" 
limit="-1" header="1"><Dataset name="snp_hopkinsBreast" 
config="snp_config_quick"><Filter 
name="snp__simple_somatic_mutation__dm__tumour_sample_id" 
value="HCC1008"/><Attribute name="cancertype"/><Attribute 
name="assemblyversion"/><Attribute 
name="snp__feature__main__chromosome"/><Attribute 
name="snp__feature__main__chromosome_start"/><Attribute 
name="snp__feature__main__chromosome_end"/><Attribute 
name="snp__simple_somatic_mutation__dm__tumour_sample_id"/><Attribute 
name="snp__simple_somatic_mutation__dm__mutation_id"/><Attribute 
name="snp__simple_somatic_mutation__dm__mutation_type"/><Attribute 
name="snp__simple_somatic_mutation__dm__tumour_genotype"/><Attribute 
name="snp__simple_somatic_mutation__dm__mutation"/><Attribute 
name="snp__simple_somatic_mutation__dm__aa_mutation"/><Attribute 
name="snp__simple_somatic_mutation__dm__is_annotated"/><Attribute 
name="snp__simple_somatic_mutation__dm__validation_status"/><Attribute 
name="snp__simple_somatic_mutation__dm__gene_affected"/><Attribute 
name="snp__simple_somatic_mutation__dm__transcript_affected"/><Attribute 
name="snp__simple_somatic_mutation__dm__consequence_type"/></Dataset></Query>

2011-06-29 09:16:13,323 INFO  [689021860@qtp-881305036-4:Log.java:165]: PSEUDO 
attribute's value: Breast Cancer (JHU, US)

2011-06-29 09:16:13,323 INFO  [689021860@qtp-881305036-4:Log.java:165]: PSEUDO 
attribute's value: NCBI36

2011-06-29 09:16:13,324 DEBUG [689021860@qtp-881305036-4:Log.java:143]: Start 
prepareLinks

2011-06-29 09:16:13,324 DEBUG [689021860@qtp-881305036-4:Log.java:143]: End 
prepareLinks

2011-06-29 09:16:13,325 DEBUG [689021860@qtp-881305036-4:Log.java:143]: 
Unplanned: 
=====================================================================================

snp_hopkinsBreast

        Attributes: snp__feature__main__chromosome 
snp__feature__main__chromosome_start snp__feature__main__chromosome_end 
snp__simple_somatic_mutation__dm__tumour_sample_id 
snp__simple_somatic_mutation__dm__mutation_id 
snp__simple_somatic_mutation__dm__mutation_type 
snp__simple_somatic_mutation__dm__tumour_genotype 
snp__simple_somatic_mutation__dm__mutation 
snp__simple_somatic_mutation__dm__aa_mutation 
snp__simple_somatic_mutation__dm__is_annotated 
snp__simple_somatic_mutation__dm__validation_status 
snp__simple_somatic_mutation__dm__gene_affected 
snp__simple_somatic_mutation__dm__transcript_affected 
snp__simple_somatic_mutation__dm__consequence_type

        Filters: snp__simple_somatic_mutation__dm__tumour_sample_id: HCC1008

-------------------------------------------------------------------------------------

Any insight would be great.


Thanks,

Heather
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