Hi Marie,

 

Thanks, so, if I can re-phrase what I think you're saying, if the
originating source (i.e. dcc.icgc.org) has an attribute hidden, even if
I unhide it on my end or create a new filter from the attribute, it
won't work because it's hidden on their end. The quick and advanced
queries are all pre-defined by the consortium. For example, the filter
under quick is not the same as the filter under advanced meaning I can't
"import from source" for the federated queries. Is that correct? 

 

Hence, why it works for advanced (set in original icgc5.xml file), but
not when I go to import and add it to quick. 

 

Thanks,

Heather

 

From: Marie Wong-Erasmus [mailto:[email protected]] 
Sent: Wednesday, June 29, 2011 10:10 AM
To: Estrella, Heather; [email protected]
Subject: Re: [BioMart Users] Adding tumour sample ID to somatic mutation
quick search in ICGC

 

Hi Heather,

 

This functionality is "correct". So if the filter is hidden in the
federated source's config, even if you turn it on locally, you will not
be able to see the filter. the only way to get around this is to import
the data to a local database and then turn the filter you want on for
all datasets using the mysql connection rather than the URL connection
as you have currently.

 

Otherwise, the other option is to ask the consortium if they don't mind
to have the filter unhidden.

 

hope this helps,

Marie

 

 

From: "Estrella, Heather" <[email protected]>
Date: Wed, 29 Jun 2011 12:34:37 -0400
To: "[email protected]" <[email protected]>
Subject: [BioMart Users] Adding tumour sample ID to somatic mutation
quick search in ICGC

 

Hi,

I'm trying to add a tumour_sample_id to both the somatic mutation and
CNV quick searches in our local ICGC-formatted biomart. The queries work
OK for local datasets, but not for any of the datasets that are
federated in from dcc.icgc.org.  The queries filtered on
"snp__simple_somatic_mutation__dm__tumour_sample_id" also work OK for
advanced queries on both federated ICGC datasets and internal datasets.

Again, technically this should work fine as can be seen in the advanced
queries, but for some reason, adding the filter to the quick search
doesn't work for federated queries. I've even compared the configs for
the advanced tumour_sample_id filter (that works) and what I have in the
quick search and they are the same.

I only get the error when adding the filter to the quick search that it
is not working. Here's the error message it returns:

2011-06-29 09:14:22,923 DEBUG [pool-1-thread-2:Log.java:143]: SENDING
INSECURE(non-OAUTH) request

text

org.biomart.common.exceptions.BioMartException: HTTP Error 400 - Filter
snp__simple_somatic_mutation__dm__tumour_sample_id not found in Breast
Cancer (JHU, US)

        at
org.biomart.queryEngine.SubQuery.executeMartServiceQuery(SubQuery.java:8
14)

        at
org.biomart.queryEngine.SubQuery.executeQuery(SubQuery.java:726)

        at
org.biomart.queryEngine.QueryRunnerThread.recurseSubQueries(QueryRunnerT
hread.java:171)

        at
org.biomart.queryEngine.QueryRunnerThread.call(QueryRunnerThread.java:73
)

        at
org.biomart.queryEngine.QueryRunnerThread.call(QueryRunnerThread.java:37
)

        at
java.util.concurrent.FutureTask$Sync.innerRun(FutureTask.java:334)

        at java.util.concurrent.FutureTask.run(FutureTask.java:166)

        at
java.util.concurrent.Executors$RunnableAdapter.call(Executors.java:471)

        at
java.util.concurrent.FutureTask$Sync.innerRun(FutureTask.java:334)

        at java.util.concurrent.FutureTask.run(FutureTask.java:166)

        at
java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.jav
a:1110)

        at
java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.ja
va:603)

        at java.lang.Thread.run(Thread.java:636)

2011-06-29 09:14:23,442 INFO  [1943435117@qtp-881305036-8:Log.java:165]:
Total query time is 520 ms

2011-06-29 09:16:13,319 INFO  [689021860@qtp-881305036-4:Log.java:165]:
Incoming XML query: <!DOCTYPE Query><Query client="webbrowser"
processor="TSV" limit="-1" header="1"><Dataset name="snp_hopkinsBreast"
config="snp_config_quick"><Filter
name="snp__simple_somatic_mutation__dm__tumour_sample_id"
value="HCC1008"/><Attribute name="cancertype"/><Attribute
name="assemblyversion"/><Attribute
name="snp__feature__main__chromosome"/><Attribute
name="snp__feature__main__chromosome_start"/><Attribute
name="snp__feature__main__chromosome_end"/><Attribute
name="snp__simple_somatic_mutation__dm__tumour_sample_id"/><Attribute
name="snp__simple_somatic_mutation__dm__mutation_id"/><Attribute
name="snp__simple_somatic_mutation__dm__mutation_type"/><Attribute
name="snp__simple_somatic_mutation__dm__tumour_genotype"/><Attribute
name="snp__simple_somatic_mutation__dm__mutation"/><Attribute
name="snp__simple_somatic_mutation__dm__aa_mutation"/><Attribute
name="snp__simple_somatic_mutation__dm__is_annotated"/><Attribute
name="snp__simple_somatic_mutation__dm__validation_status"/><Attribute
name="snp__simple_somatic_mutation__dm__gene_affected"/><Attribute
name="snp__simple_somatic_mutation__dm__transcript_affected"/><Attribute
name="snp__simple_somatic_mutation__dm__consequence_type"/></Dataset></Q
uery>

2011-06-29 09:16:13,323 INFO  [689021860@qtp-881305036-4:Log.java:165]:
PSEUDO attribute's value: Breast Cancer (JHU, US)

2011-06-29 09:16:13,323 INFO  [689021860@qtp-881305036-4:Log.java:165]:
PSEUDO attribute's value: NCBI36

2011-06-29 09:16:13,324 DEBUG [689021860@qtp-881305036-4:Log.java:143]:
Start prepareLinks

2011-06-29 09:16:13,324 DEBUG [689021860@qtp-881305036-4:Log.java:143]:
End prepareLinks

2011-06-29 09:16:13,325 DEBUG [689021860@qtp-881305036-4:Log.java:143]:
Unplanned:
========================================================================
=============

snp_hopkinsBreast

        Attributes: snp__feature__main__chromosome
snp__feature__main__chromosome_start snp__feature__main__chromosome_end
snp__simple_somatic_mutation__dm__tumour_sample_id
snp__simple_somatic_mutation__dm__mutation_id
snp__simple_somatic_mutation__dm__mutation_type
snp__simple_somatic_mutation__dm__tumour_genotype
snp__simple_somatic_mutation__dm__mutation
snp__simple_somatic_mutation__dm__aa_mutation
snp__simple_somatic_mutation__dm__is_annotated
snp__simple_somatic_mutation__dm__validation_status
snp__simple_somatic_mutation__dm__gene_affected
snp__simple_somatic_mutation__dm__transcript_affected
snp__simple_somatic_mutation__dm__consequence_type

        Filters: snp__simple_somatic_mutation__dm__tumour_sample_id:
HCC1008

------------------------------------------------------------------------
-------------

Any insight would be great.

 

Thanks,

Heather

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