>Of kilopascal >Aspirin tablets were once 325 mg (5 grain), but at least Bayer >and Anacin have upped the dosage to at least 400 mg. >And with that change, the grains are no longer stated.
A change in the law from 'approximate' to 'exact' equivalent amounts might have encouraged them to only use metric. [begin quote] Prior to USP XX and NF XV, the official compendia allowed the approximate equivalent of the exact quantity to be enclosed in parenthesis; such as Quinidine Sulfate 200 mg. (3 grains). On July 1, 1980 the USP XX and NF XV became official and requires that "Where expressed in both the metric and apothecary systems, statements of quantity or strength in the labeling of drug products shall utilize the exact equivalent." (See inside back cover USP XX and NF XV). Therefore the above example would now have to be modified to read Quinidine Sulfate 200 mg (3.086 grains). [end quote] http://www.mlmlaw.com/library/guides/fda/compguides/humandrugs.htm
