понедельник, 16 декабря 2013 г., 20:04:38 UTC+4 пользователь Christoph 
Junghans написал:
>
> 2013/12/16 Sergey Larin <[email protected] <javascript:>> 
> > 
> > Dear Sikandar, 
> > 
> > Thank you for your help. I've done everything you describe already. I've 
> prepared mapping and topology files and start test IBI process. I'll try to 
> describe problem that exists, from my point of view in more details. 
> > Let's use notation proposed by you and see at A-B distribution. Monomer 
> unit of my polymer consists of 11 beads that have 4 different types: 
> -C1-D1-A1-D1-C1-B1-A2-B2-B3-A3-B4- 
> > This topology is described in VOTCA mapping file that I use to calculate 
> distributions with csg_stat. Of course, it excludes interactions for beads 
> bonded directly. for example, A2-B2 and B3-A3 pairs are not included in 
> distribution. This is right. But it should also exclude pairs in which 
> beads are connected by two consecutive bonds, for example, A2-B3 and B2-A3, 
> but csg_stat does not do this exclusion. That is why I have the peak on the 
> A-B pair distribution function. And this is a problem. 
> > As far as I know, Gromacs does not calcuate non-bonded interactions for 
> beads connected by one, two and three consecutive bonds, thus only 
> interactions between pairs B1-A3 and A2-B4 are calculated during 
> simulation. Thus, only these two pairs should be taken into account when 
> calculation distribution, and csg_stat does not do this. 
> > 
> > So, my question is how to exclude 1-3 and 1-4 pairs from distributions 
> calculated by csg_stat? Is it possible at all? Unfortunately I've not found 
> any solutions neither in manual, nor in tutorial samples. 
> VOTCA has no way to define the number of consecutive bonds to exclude, 
> but you can create a couple of extra bonds and angles to achieve the 
> same number of exclusions. 
>
>
O'K. Thanks. Could you say which atoms are excluded by csg_stat? Connencted 
by bonds and included in angles and dihedrals? If it so, I'll define 
additional dihedral angles in my simulation and it should solve the problem.

Sergey

Cheers, 
>
> Christoph 
> > 
> > Sincerely, 
> > Sergey 
> > 
> > 
> > суббота, 14 декабря 2013 г., 0:41:51 UTC+4 пользователь sikandar 
> написал: 
> >> 
> >> Hi Sergey 
> >> 
> >> From your description of the problem, I understand that you want to use 
> csg_stat to compute 
> >> only the non-bonded distributions between specified atoms. Right? 
> >> 
> >> If so.. csg_stat can be used to compute both bonded and non-bonded 
> distributions separately. 
> >> To achieve that one approach would be to specify your molecule topology 
> that each atom has 
> >> unique and different name though there may be multiple atoms of same 
> type. In your monomer case, 
> >> there are four different types of atoms A, B, C, D, and each monomer 
> consists of 2 As, 3 Bs, 2Cs, and 2 Ds. 
> >> Then, in topology, you can specify atom types as A, B, C, D and atom 
> names are A1, A2, B1, B2, B3, C1, C2, 
> >> and D1, and D2. For clarification, you can check out the propane 
> example in votca-tutorials. 
> >> 
> >> Now with above mentioned topolopy, you can compute non-bonded 
> distributions between A1-A2, C1-C2, and so on. 
> >> 
> >> Next, if you want to perform coarse-graining and need a reference pair 
> distributions then first you need to define 
> >> a mapping to specify how to determine CG beads configurations from a 
> given reference all-atom configuration. Then 
> >> you can provide this mapping file to csg_stat to determine target 
> distributions for coarse-graining. 
> >> Again you can check out propane example and votca manual to get more 
> information about how to achieve this. 
> >> 
> >> I hope this helps. 
> >> 
> >> Cheers 
> >> Sikandar 
> >> 
> >> 
> >> On Fri, Dec 13, 2013 at 3:36 AM, Sergey Larin <[email protected]> 
> wrote: 
> >>> 
> >>> Dear votca users, 
> >>> 
> >>> I've faced one more problem (not so big, I suppose) in coarsegrainig 
> using votca. I've found that csg_stat calculate pair distribution functions 
> taking into account atoms that are bonded. As a result the distributions 
> have peaks that correspond to bonded interaction (see the picture, in the 
> molecule I'm coarsegraining the monomer unit is -C-D-A-D-C-A-B-B-A-B-). It 
> is clear for me that it is pretty useless to perform IBI for non-bonded 
> interactions using these distribution as target ones. Thus, my question is 
> how to say csg_stat to exclude bonded atoms from distribution caclulations? 
> Unfortunately, I've found only the way to create exclusion list for 
> non-bonded interactions to perform reference simulations for bonded 
> interactions distributions. 
> >>> 
> >>> Thanks in advance. 
> >>> 
> >>> Sincerely, 
> >>> Sergey 
> >>> 
> >>> 
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>
> -- 
> Christoph Junghans 
> Web: http://www.compphys.de 
>

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