2015-11-12 5:51 GMT-07:00 Rom <[email protected]>:
> Hello all!
>
> I have a small query, and I couldn't find it anywhere else on this page.
>
> I'm doing hybrid FM of hexane (256 molecules in a box), where boltzmann
> inversion for the bonded, and FM for the non-bonded.
> My simulation appeared to show all of my hexane molecules clumping together
> (literally a giant ball of dense hexanes).
>
> I compared my non bonded potential e.g. A-A, to the potential given in the
> paper:
>
> Victor Ruehle, Christoph Junghans, Macrolmol. Theory Simul. 2011, 20,
> 472-477 (Hybrid approaches to coarse-graining using the VOTCA package:
> Liquid Hexane)
>
> I have an attractive well depth of -20kj/mol (attached, plot column 1 and
> 6), whereas the potential in the paper has a well depth of -1 kj/mol, so
> mine is far too attractive (which explains the extreme aggregation)! Even my
> slight repulsive bump at the zero line is almost 0.8 kj/mol.
>
> Is there any obvious reason why my potential could be this off? Is it an
> effect of maybe how I choose my grid size, or blocking averages when force
> matching?
Did you follow the hexane/hybrid_force_matching tutorial?
<https://github.com/votca/csg-tutorials/tree/master/hexane/hybrid_force_matching>

Grid size, or blocking averages when force matching only matter if you
running low on statistics.
I seems to me, you might have forgot to the rerun step using mdrun to
subtract the force.

Christoph

>
> If you need anymore files or details, please just let me know, I will be
> happy to provide them! and thank you for all the help :D
>
> Many thanks
> Rom
>
>
>
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-- 
Christoph Junghans
Web: http://www.compphys.de

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