2015-11-16 6:32 GMT-07:00 Rom <[email protected]>:
>
>
> On Thursday, 12 November 2015 18:28:25 UTC, Christoph Junghans wrote:
>>
>> 2015-11-12 5:51 GMT-07:00 Rom <[email protected]>:
>> > Hello all!
>> >
>> > I have a small query, and I couldn't find it anywhere else on this page.
>> >
>> > I'm doing hybrid FM of hexane (256 molecules in a box), where boltzmann
>> > inversion for the bonded, and FM for the non-bonded.
>> > My simulation appeared to show all of my hexane molecules clumping
>> > together
>> > (literally a giant ball of dense hexanes).
>> >
>> > I compared my non bonded potential e.g. A-A, to the potential given in
>> > the
>> > paper:
>> >
>> > Victor Ruehle, Christoph Junghans, Macrolmol. Theory Simul. 2011, 20,
>> > 472-477 (Hybrid approaches to coarse-graining using the VOTCA package:
>> > Liquid Hexane)
>> >
>> > I have an attractive well depth of -20kj/mol (attached, plot column 1
>> > and
>> > 6), whereas the potential in the paper has a well depth of -1 kj/mol, so
>> > mine is far too attractive (which explains the extreme aggregation)!
>> > Even my
>> > slight repulsive bump at the zero line is almost 0.8 kj/mol.
>> >
>> > Is there any obvious reason why my potential could be this off? Is it an
>> > effect of maybe how I choose my grid size, or blocking averages when
>> > force
>> > matching?
>> Did you follow the hexane/hybrid_force_matching tutorial?
>>
>> <https://github.com/votca/csg-tutorials/tree/master/hexane/hybrid_force_matching>
>>
>> Grid size, or blocking averages when force matching only matter if you
>> running low on statistics.
>> I seems to me, you might have forgot to the rerun step using mdrun to
>> subtract the force.
>>
>
> Hi Christoph! Thank you for the reply!
> OK, so its not grid size or blocking averages (I am using around 5000 force
> outputs).
> Yes! I've been using the hexane tutorial as my base, looking at all the
> scripts etc. And I did output the individual force interactions using -rerun
> (by using energygrp_excl in the mdp file (attached)), and running the
> following gromacs command.
>
> grompp_mpi -f md_AA.mdp -c heat0_npt10.gro -p topol.top -n index.ndx -o
> npt_prod_AA.tpr -maxwarn 1
> mpirun -n $SLURM_NTASKS mdrun_mpi -rerun npt_production.trr -v -deffnm
> npt_prod_AA
>
> [where md_AA.mdp is the specific mdp file for my AA interaction,
> heat0_npt10.gro is my original .gro file, and npt_production.trr is the
> original trajectory file which includes all the interactions, which I am now
> trying to only specify for AA interactions using -rerun}
>
> Can you see any obvious mistake, since its such a simple system, I'm
> struggling to see what the issue is?
> (Also, I'm unsure if this is a gromacs issue, or a VOTCA issue, so I
> apologise!)
I don't really have a good idea right now, did you try the original
example to check if that works?

Christoph
>
>
>
>
>
>
>>
>> Christoph
>>
>> >
>> > If you need anymore files or details, please just let me know, I will be
>> > happy to provide them! and thank you for all the help :D
>> >
>> > Many thanks
>> > Rom
>> >
>> >
>> >
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>>
>>
>>
>> --
>> Christoph Junghans
>> Web: http://www.compphys.de
>
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-- 
Christoph Junghans
Web: http://www.compphys.de

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