On Thu, Feb 20, 2020 at 10:29 AM Ali Khodayari <[email protected]> wrote:
>
> Dears,
>
>
>
> I am trying to derive potentials for a CG cellobiose-water system. I am using 
> IBI. The non-bonded interactions are derived using the distributions taken 
> from csg_stat, and I am trying to use csg_boltzmann to get the potentials for 
> bonded interactions.
>
>
>
> As the simulations crash at the very first step of the iteration, I tried to 
> add the potentials one by one (first bonds, then angles, and at the end 
> dihedrals).
>
>
>
> An error which I face regularly is:
>
>
>
> A tabulated bond interaction table number 1 is out of the table range: r
>
> 0.501462, between table indices 501 and 502, table length 501
>
>
>
> I believe this is due to high forces between atoms at some point, shooting 
> the atoms to distances higher than the table’s length.
>
>
>
> After solving the issues with the bonds and angles, I am now trying to get a 
> nice potential for the dihedrals in my system. Yet, the potentials for the 
> dihedrals always look very weird (see table_d1.xvg). Without including this 
> table, the simulations in gromacs at least run for 1000 steps (1ps), but 
> including this crashes the simulations at the very first step. I am using the 
> following commands for csg_boltzmann:
>
>
>
> csg_boltzmann --cg "cellobiose.xml;water.xml" --top md_at.tpr --trj md_at.trr 
> < boltzmann_cmds2
>
>
>
> having Boltzmann_cmds as:
>
>
>
> tab set T 300
>
> tab set smooth_pot 1
>
> tab set n 101
>
> tab dihedral_yrry.pot *:dihedral-YRRY:*
>
> q
>
>
>
> The output is already looking very strange (see dihedral_yyry.pot)
>
> Then I use the following commands to get the table:
>
>
>
> BOND_FILE=$"dihedral_yrry.pot"
>
> SETTINGS="convert_dihedral.xml"
>
>
>
> # cut bad sampled regions at the boundaries
>
> sed -e '1,33d' -e 's/$/ i/' $BOND_FILE | tac | sed -e '1,0d' | tac > 
> "$BOND_FILE.cut"
>
>
>
> csg_call table smooth "$BOND_FILE.cut" "$BOND_FILE.smooth"
>
> csg_resample --in "$BOND_FILE.smooth" --out "$BOND_FILE.refined" --grid 
> 0:0.001:3.135
>
> csg_call table extrapolate --function quadratic --region left 
> "$BOND_FILE.refined" "$BOND_FILE.refined1"
>
> csg_call table extrapolate --function quadratic --region right 
> "$BOND_FILE.refined1" "$BOND_FILE.cur"
>
> csg_call --ia-type dihedral --ia-name dihedral --options $SETTINGS 
> convert_potential gromacs "$BOND_FILE.cur" table_d${2}.xvg
>
>
>
> and the .xml file looks like this:
>
>
>
> <cg>
>
>   <bonded>
>
>       <bondtype>dihedral</bondtype>
>
>     <name>dihedral</name>
>
>     <min>0</min>
>
>     <max>3.1415</max>
>
>     <step>0.001</step>
>
>     <inverse>
>
>       <gromacs>
>
>         <table>table_d1.xvg</table>
>
>       </gromacs>
>
>     </inverse>
>
>   </bonded>
>
>
>
>   <inverse>
>
>     <gromacs>
>
>       <pot_max>1e6</pot_max>
>
>       <table_end>3.1415</table_end>
>
>       <min>0.0</min>
>
>       <max>3.1415</max>
>
>       <table_bins>0.004</table_bins>
>
>     </gromacs>
>
>   </inverse>
>
> </cg>
>
>
>
> I have tried to cut different edges of the potential, but they all seem not 
> logical to me, and moreover, cause the simulation to crash at the very 
> beginning.
>
>
>
> Would you please kindly let me know if I am doing something wrong and/or how 
> I can resolve this issue?
All that looks pretty reasonable to me, we recently found a bug in
dihedral potential conversion see:
https://github.com/votca/csg/pull/500
but in general dihedral IBI is pretty still pretty experimental in IBI
and we should most likely add a warning about that to the code.
I, personally, have not worked with dihedral potentials enough to give
any advice on this matter.

Christoph
>
>
>
> My best,
>
> Ali
>
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-- 
Christoph Junghans
Web: http://www.compphys.de

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