Hi there, I get this question all the time. End of the day, what matters most to clients is rapid deployment and low cost of software maintenance in addition to nailing their requirements. I have deployed Web2Py in companies and top hospitals across the US, within their corporate IT groups. Be confident of your capabilities and you will be able to sell any solution you want.
Earlier this year, I had posted a note about w2p, which highlights the advantages of this light and efficient platform: https://groups.google.com/d/topic/web2py/xlIjCReudhw/discussion Good luck with your projects! -Sebastian