Try telneting to the SMTP port (25)  to make certain it isn't blocked.  
Your ISP may be blocking port 25 (most of them are these days).

i.e. telnet mail.yourdomain.com 25

or by ip

telnet xx.xxx.xxx.xx 25

Jeff

Larry Azlin wrote:

>Greetings.
>
>I run Xmail 1.21 on a SUSE 9.0 box to host my personal email
>(azlin.com), and all's well if the laptop running my email client
>(Thunderbird) is on my LAN.  Recently I've been taking the laptop over
>to a friend's house and trying to send email from there, w/o success. 
>I can GET email from my Xmail server, I just can't SEND through it.
>
>I've modified smtprelay.tab to include the ip at my friend's house, so
>it now looks like:
>
>"192.168.0.0"[TAB]"255.255.0.0"
>"xxx.xxx.xxx.0"[TAB]"255.255.255.0"
>
>And I've verified that smtp.ipmap.tab is correct:
>
>"0.0.0.0"[TAB]"0.0.0.0"[TAB]"ALLOW"[TAB]1
>
>Just to be sure, I've also looked at my pop3 log files and verified
>that I've got his ip address correct.  Yet, when I try to send email,
>there's a long delay while Thunderbird is trying to send, and I get an
>"unable to access server" type of message.  I'm betting that there's
>something simple which I need to do in addition to the above changes
>.... can anyone point me in the right direction?
>
>TIA,
>Larry Azlin
>
>P.S.  I restarted Xmail after these changes.
>
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