Dear All, I have a question regarding the methyl RDC. This is in connection with the answer posted by Prof. Clore (dated Dec 11, 2003) as an answer to Dr. Andrew's Mail. It has been given in the answer that for methyl RDCs, for instance, in the case of Ala, we have to use CA-CB in the selection. It has also been mentioned in the paper by Ottiger et al ( JMR 365 1998) that the gyromagnetic ratio and bond distance for methyl group will be absorbed by xplor routine. I am bit confused, because, if we use CA-CB for Ala methyl, how can we differentiate RDC from methyl group and that is from CA-CB itself.
I will be very much thankful, if you can clariful me doubt. Thank you in advance. Sincerely, Thenmalar
