Ten Years After Dolly, Animal Cloning Realizes Significant Milestones 
and Progress 
Technology Poised to Begin Providing Consumers With Improved Products 
and Benefits 

In the decade since scientists at Scotland's Roslin Institute first 
announced that they had successfully cloned the first animal from an 
adult cell — a sheep named Dolly — animal cloning technology has 
substantially advanced and will soon begin offering consumers 
innovative and unique products and benefits. 

"Ten years ago today, there occurred a dramatic moment in the world 
of biotechnology when Dolly's successful birth was announced," said 
Jim Greenwood, president and chief executive officer of the 
Biotechnology Industry Organization (BIO). "Since Dolly, animal 
cloning technology has advanced significantly. Researchers have 
developed improved and safer cloning techniques that have resulted in 
normal births of healthy animal clones, and we are now applying this 
technology to a variety of applications. Today we are poised to 
utilize this technology to enhance food production, food security in 
developing countries, the health of farm animals and the safety of 
our food supply. Cloning will also tackle the challenge of the 
extinction of wild animals like the giant panda." 

Dolly was the first mammal to be successfully cloned using somatic 
cell nuclear transfer (SCNT) technology. This technique makes it 
possible to produce multiple animals from a single donor, and 
involves transferring the genetic information from a cell from the 
body of an animal into an empty oocyte, or egg. This process results 
in an embryo, which is implanted into a surrogate mother, who carries 
the pregnancy to term. 

Animal cloning is an assisted reproductive technology that allows 
livestock breeders and farmers to produce identical twins of their 
best animals. In December 2006, the U.S. Food and Drug Administration 
(FDA) released a draft risk assessment which concluded that meat and 
milk products from animal clones and their offspring are safe for 
human consumption, and are no different from foods produced through 
other breeding methods. While currently there are no known products 
from animal clones and their offspring on the market, in the future, 
consumers will benefit from a healthier, consistent, and more 
abundant meat and milk supply produced from animal cloning. 

In the decade since Dolly's birth, scientists have successfully 
cloned over a dozen other species. These include cows, goats, pigs, 
horses, mules, deer, mice, cats, dogs, and rare and endangered 
species including the mouflon, gaur, banteng, and African wildcat. 
These advances were made possible by significant improvements in 
cloning techniques, which have also resulted in a decrease in unique 
health risks to animal clones. Decades of research and improvement in 
cloning techniques have resulted in the production of animal clones 
that are as healthy as conventional animals and those conceived 
through other forms of assisted reproductive technology. 

"Cloning technology has enormous potential to positively impact the 
world in which we live," Greenwood stated. "This technology gives us 
the opportunity to increase community health and well-being by 
providing people in developing countries with greater access to 
protein-rich animal food products. Farmers have an opportunity to 
meet consumer demand for high quality and safe food that is available 
in a reliable and consistent manner and conservationists have a 
fighting chance to preserve endangered animal species." 

Scientific resources on animal cloning can be found at 
www.CloneSafety.org. 

BIO represents more than 1,100 biotechnology companies, academic 
institutions, state biotechnology centers and related organizations 
across the United States and 31 other nations. BIO members are 
involved in the research and development of health-care, 
agricultural, industrial and environmental biotechnology products. 

Advance media registration for the BIO International Convention is 
now available online. Registration is complimentary for credentialed 
members of the news media. To register, please visit 
www.bio2007.org/Media. Reporters and editors working full-time for 
print or broadcast news organizations may register onsite with valid 
media credentials. All freelancers, college and online publications 
are strongly encouraged to register in advance by Friday, April 20, 
2007. 



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