If it does what it claims – incredibly impressive. The issue we have is there is no way to verify or validate the claims it is making.
The letter is a call and start of a conversation about how the ever-changing landscape of communication and publication of science should be. -Stephanie Wankowicz ________________________________ From: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK> on behalf of Krieger, James M <krieg...@pitt.edu> Sent: Monday, May 13, 2024 10:22 AM To: CCP4BB@JISCMAIL.AC.UK <CCP4BB@JISCMAIL.AC.UK> Subject: Re: [ccp4bb] Fwd: AlphaFold3 Transparency and Reproducibility It definitely is impressive but it also has clear limitations On 13 May 2024, at 15: 22, Sylvia Fanucchi <0000d0c4e77ae410-dmarc-request@ jiscmail. ac. uk> wrote: You don't often get email from 0000d0c4e77ae410-dmarc-request@ jiscmail. ac. uk. ZjQcmQRYFpfptBannerStart This Message Is From an External Sender This message came from outside your organization. ZjQcmQRYFpfptBannerEnd It definitely is impressive but it also has clear limitations On 13 May 2024, at 15:22, Sylvia Fanucchi <0000d0c4e77ae410-dmarc-requ...@jiscmail.ac.uk> wrote: You don't often get email from 0000d0c4e77ae410-dmarc-requ...@jiscmail.ac.uk. Learn why this is important<https://urldefense.com/v3/__https://aka.ms/LearnAboutSenderIdentification__;!!LQC6Cpwp!ojUwuRRzsCarUF-wwnVWIQtQbTonf10zBas4dHDOMDcNF3qWUSO99i3QLLB39nBZ8NEnc9RG_drv9T5at5d7AmVluUFn$> Is it just me who is really impressed by it? Am I missing something? Get Outlook for Android<https://urldefense.com/v3/__https://aka.ms/AAb9ysg__;!!LQC6Cpwp!ojUwuRRzsCarUF-wwnVWIQtQbTonf10zBas4dHDOMDcNF3qWUSO99i3QLLB39nBZ8NEnc9RG_drv9T5at5d7ArXNQatL$> ________________________________ From: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK> on behalf of Rafael Marques <rafael_mmsi...@hotmail.com> Sent: Monday, May 13, 2024 3:13:16 PM To: CCP4BB@JISCMAIL.AC.UK <CCP4BB@JISCMAIL.AC.UK> Subject: Re: [ccp4bb] Fwd: AlphaFold3 Transparency and Reproducibility I tried it yesterday and I was really shocked by how fast it is. When I was preparing to submit my second job, the first one was already finished, which made me think that I was definitely doing something wrong. Probably I was... Best wishes Rafael Marques On 13 May 2024 09:53, Harry Powell <0000193323b1e616-dmarc-requ...@jiscmail.ac.uk> wrote: Hi folks This arrived in my inbox this morning, and I believe that it may provoke some discussion… Wikipedia tells me: στέργει γὰρ οὐδεὶς ἄγγελον κακῶν ἐπῶν Best wishes! Harry > From: Stephanie Wankowicz <mullane.stepha...@gmail.com> > Sent: Saturday, May 11, 2024 3:31 PM > To: James Fraser <jaimefra...@gmail.com>; Pedro Beltrao > <pedrobelt...@gmail.com>; Benjamin Cravatt <crav...@scripps.edu>; Roland > Dunbrack <roland.dunbr...@gmail.com>; Anthony Gitter > <git...@biostat.wisc.edu>; Kresten Lindorff-Larsen <lindo...@bio.ku.dk>; > Sergey Ovchinnikov <s...@mit.edu>; Polizzi, Nicholas F. > <nicholasf_poli...@dfci.harvard.edu>; Brian Shoichet <bshoic...@gmail.com> > Subject: AlphaFold3 Transparency and Reproducibility > > > This email from mullane.stepha...@gmail.com originates from outside > Imperial. Do not click on links and attachments unless you recognise the > sender. If you trust the sender, add them to your safe senders list > <https://spam.ic.ac.uk/SpamConsole/Senders.aspx><https://urldefense.com/v3/__https://spam.ic.ac.uk/SpamConsole/Senders.aspx*3E__;JQ!!LQC6Cpwp!ojUwuRRzsCarUF-wwnVWIQtQbTonf10zBas4dHDOMDcNF3qWUSO99i3QLLB39nBZ8NEnc9RG_drv9T5at5d7AkQKssvO$> > to disable email stamping for this address. > > Hello, > > > As many of you, we were incredibly disappointed with the lack of code or > even executables accompanying the publication of AlphaFold3 in Nature. > AlphaFold3 was released without the means to test and use the software in a > high-throughput manner. This does not align with the principles of scientific > research, which rely on the ability of the community to evaluate, use, and > build upon existing work. > > > > We have written a letter, which will be posted on Zenodo and submitted as > a Letter to the Editor in the coming days. > > > > Please see the entire letter here. > <https://docs.google.com/forms/d/e/1FAIpQLSf6ioZPbxiDZy5h4qxo-bHa0XOTOxEYHObht0SX8EgwfPHY_g/viewform?usp=sf_link><https://urldefense.com/v3/__https://docs.google.com/forms/d/e/1FAIpQLSf6ioZPbxiDZy5h4qxo-bHa0XOTOxEYHObht0SX8EgwfPHY_g/viewform?usp=sf_link*3E__;JQ!!LQC6Cpwp!ojUwuRRzsCarUF-wwnVWIQtQbTonf10zBas4dHDOMDcNF3qWUSO99i3QLLB39nBZ8NEnc9RG_drv9T5at5d7AqTp0-CX$> > If you want to endorse this letter, please fill out your name, affiliation, > and email in the form. > > > > Additionally, a PDF version of the letter can be found here > <https://drive.google.com/file/d/1u1D3KzsllpI_6I0drA9RdIiENd9EK1Hz/view?usp=sharing><https://urldefense.com/v3/__https://drive.google.com/file/d/1u1D3KzsllpI_6I0drA9RdIiENd9EK1Hz/view?usp=sharing*3E__;JQ!!LQC6Cpwp!ojUwuRRzsCarUF-wwnVWIQtQbTonf10zBas4dHDOMDcNF3qWUSO99i3QLLB39nBZ8NEnc9RG_drv9T5at5d7AmjNPgIH$>. > > > > Thank you, > > > > Stephanie Wankowicz, UCSF > > Pedro Beltrao, ETH > Benjamin Cravatt, Scripps > Roland Dunbrack, FCCC > Anthony Gitter, UW Madison > Kresten Lindorff-Larsen, Copenhagen > Sergey Ovchinnikov, MIT > Nicholas Polizzi, DFCI/HMS > Brian Shoichet, UCSF > James Fraser, UCSF > > ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1<https://urldefense.com/v3/__https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1__;!!LQC6Cpwp!ojUwuRRzsCarUF-wwnVWIQtQbTonf10zBas4dHDOMDcNF3qWUSO99i3QLLB39nBZ8NEnc9RG_drv9T5at5d7AoA8pumq$> This message was issued to members of www.jiscmail.ac.uk/CCP4BB<https://urldefense.com/v3/__http://www.jiscmail.ac.uk/CCP4BB__;!!LQC6Cpwp!ojUwuRRzsCarUF-wwnVWIQtQbTonf10zBas4dHDOMDcNF3qWUSO99i3QLLB39nBZ8NEnc9RG_drv9T5at5d7AgFZZaeK$>, a mailing list hosted by www.jiscmail.ac.uk<https://urldefense.com/v3/__http://www.jiscmail.ac.uk__;!!LQC6Cpwp!ojUwuRRzsCarUF-wwnVWIQtQbTonf10zBas4dHDOMDcNF3qWUSO99i3QLLB39nBZ8NEnc9RG_drv9T5at5d7An7YNOzL$>, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/<https://urldefense.com/v3/__https://www.jiscmail.ac.uk/policyandsecurity/__;!!LQC6Cpwp!ojUwuRRzsCarUF-wwnVWIQtQbTonf10zBas4dHDOMDcNF3qWUSO99i3QLLB39nBZ8NEnc9RG_drv9T5at5d7ApCXqJeM$> ________________________________ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1<https://urldefense.com/v3/__https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1__;!!LQC6Cpwp!ojUwuRRzsCarUF-wwnVWIQtQbTonf10zBas4dHDOMDcNF3qWUSO99i3QLLB39nBZ8NEnc9RG_drv9T5at5d7AoA8pumq$> This communication is intended for the addressee only. 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