Re: [ccp4bb] am I doing this right?

2021-10-15 Thread Gergely Katona
Dear James, Uniform distribution sounds like “I have no idea”, but a uniform distribution does not go from -inf to +inf. If I believe that every count from 0 to 65535 has the same probability, then I also expect counts with an average of 32768 on the image. It is not an objective belief in the

[ccp4bb] Structural Biology researcher position at St. Jude

2021-10-15 Thread Marcus Fischer
The lab of Dr. Taosheng Chen is recruiting a Structural Biologist to join the efforts in structural determination of protein-ligand complexes and contribute structural biology insights into the mechanism of action of novel chemical probes. The Chen Laboratory (https://www.stjude.org/chen) uses

Re: [ccp4bb] am I doing this right?

2021-10-15 Thread James Holton
Well I'll be... Kay Diederichs pointed out to me off-list that the k+1 expectation and variance from observing k photons is in "Bayesian Reasoning in Data Analysis: A Critical Introduction" by Giulio D. Agostini. Granted, that is with a uniform prior, which I take as the Bayesean equivalent

[ccp4bb] PDB-REDO downtime

2021-10-15 Thread Robbie Joosten
Dear BB-ers, Due to electrical maintenance at our host institute pdb-redo.eu will be unavailable from 20:00h (Amsterdam) on October 15th to roughly 12:30h on October 16th. Apologies for the inconvenience. Best wishes, Robbie Joosten