Re: [ccp4bb] Fragile Crystals

2023-11-22 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Hi Elizabeth, As suggested VMXi at Diamond may be able to help with in situ data collection without harvesting. I'd be happy to discuss if useful? cheers Mike Sent from Outlook for Android From: CCP4 bulletin board on behalf of CCP4BB

Re: [ccp4bb] Crystallisation textbook

2023-07-14 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Of course, having sent this email I found the third edition of the same book from 2021. I would still be grateful for other suggestions though Mike rom: CCP4 bulletin board On Behalf Of Hough, Michael (DLSLtd,RAL,LSCI) Sent: Friday, July 14, 2023 3:19 PM To: CCP4BB@JISCMAIL.AC.UK Subject

[ccp4bb] Crystallisation textbook

2023-07-14 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Hi all, I'd be grateful for any recommendations of a good up-to-date textbook covering macromolecular crystallisation. Currently we are using the excellent book by Terese Bergfors (2009) but would be interested if there is anything more recent with discussion around automation,

[ccp4bb] Postdoctoral position in room temperature fragment screening by X-ray crystallography

2023-02-22 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Dear ccp4 community, We are recruiting for a postdoctoral position at Diamond to work on developing room temperature fragment screening as a tool in drug discovery. This is part of a major international project funded by Horizon-Europe (see link below) so has a lot of opportunity for

[ccp4bb] Access to Diamond VMXi (room temperature beamline) via iNEXT

2023-02-21 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Hi all, We are now accepting applications for in situ plate-based data collection beamtime at VMXi, Diamond, for access through the iNEXT-Discovery project. This access route provides funded access to Diamond for EU users. Existing users do not need to reapply

[ccp4bb] PHD studentship in inhibitor/fragment binding crystallography with cancer target proteins at room temperature

2022-10-18 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Dear all, There is a PhD studentship opportunity at the Institute of Cancer research, London in partnership with Diamond. This would be to start in October 2023 This project is to explore the binding of inhibitors and fragments to the cancer drug target proteins BCL6 and HSP70 using

[ccp4bb] Data analysis PDRA position at VMXi, Diamond

2022-04-27 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Dear CCP4bb-ers, We are readvertising this postdoctoral post at beamline VMXi, Diamond Light Source and I would be very grateful if you could pass it on to potentially suitable candidates. This post would potentially suit somebody within a physics or computer science department as well as in

[ccp4bb] PhD studentship in time resolved crystallography of multifunctional enzymes using synchrotron and XFEL facilities

2022-03-14 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Dear all, We have extended the deadline for the studentship and will now consider applications as they are received with no fixed closing dates. I will be very grateful if you could pass this on to any potentially interested candidates. We have a fully funded four year PhD studentship

[ccp4bb] PhD studentship in time resolved crystallography of multifunctional heme enzymes

2022-01-21 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Hi all, We have a four year PhD studentship available from October 2022, as a joint project between Diamond and the University of Essex in Colchester. The project is to use time resolved crystallography to study enzyme reactions and mechanisms in multifunctional heme enzymes. Reactions will be

Re: [ccp4bb] JCSG structure validation server - Quality Control Check v3.2 for X-ray and cryo-EM structures

2022-01-12 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Gye Won Tomek Robin From: CCP4 bulletin board mailto:CCP4BB@JISCMAIL.AC.UK>> on behalf of Hough, Michael (DLSLtd,RAL,LSCI) <69715b1ac6c0-dmarc-requ...@jiscmail.ac.uk<mailto:69715b1ac6c0-dmarc-requ...@jiscmail.ac.uk>> Sent: Thursday, December 2, 2021 9:37 AM To: CCP4BB@JISCM

Re: [ccp4bb] JCSG structure validation server

2021-12-02 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Thanks to everyone who has answered my question, look forward to hearing if the server is revived in the future! Best wishes, Mike From: CCP4 bulletin board On Behalf Of Hough, Michael Sent: 01 December 2021 14:13 To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] JCSG structure validation server

[ccp4bb] PDRA position available in the Hough group at Diamond Light Source

2021-10-06 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Dear CCP4 community, I'd be grateful is you could pass on the below advert to any potentially suitable candidates: We are searching for a PDRA level scientist to join the Hough group at Diamond Light Source to carry out state-of-the-art structural biology and biochemical investigations into