Re: [ccp4bb] Refining a crystal structure with (very) high solvent content

2017-06-02 Thread Dale Tronrud
On 6/2/2017 1:42 PM, wtempel wrote: > Hello all, > crystals with high solvent content tend to diffract poorly, at least > according to intuition. Several years ago we solved a structure > that > appeared to buck that trend with a

Re: [ccp4bb] Refining a crystal structure with (very) high solvent content

2017-06-02 Thread Robbie Joosten
Hi Wolfram, We recently moved pdb-redo to a new domain, so the entry you are interested in is at https://pdb-redo.eu/db/2h58 This entry at 1.85A resolution was indeed refined with anisotropic B-factors based on the Hamilton R ratio test. There was no paired refinement for this entry. We only

[ccp4bb] Fwd: biotech opportunity

2017-06-02 Thread Diana Tomchick
From: Steven McKnight > Subject: favor Date: June 2, 2017 at 3:21:39 PM CDT To: Michael Rosen > Cc: Joseph Ready

[ccp4bb] Postdoc Position in Structural Biology at UNL

2017-06-02 Thread limei zhang
Hi all, A Postdoc position is available in my group at University of Nebraska - Lincoln, USA on July 1st 2017. The position will be highly suitable for somebody with experience in structural biology (Xray crystallography or NMR). For more details, please see here:

[ccp4bb] Postdoctoral fellow position at Sanofi

2017-06-02 Thread Joseph Batchelor
Dear CCP4 community, We are pleased to announce an opening in our Boston area structural biology group for a postdoctoral scholar conducting cryo-electron microscopy and protein crystallography research. A formal job listing is found at

Re: [ccp4bb] help needed to interpret a SRF

2017-06-02 Thread R. Michael Garavito
Vincent, You are on the right track. Notice now that both maps at chi/kappa=180 have strong peaks at the y-axis and a “mirror” plane perpendicular to this.This is what would be expected for P21, i.e., Y is b/b*. Then depending on the orthogonalization convention of MolRep, the a- and

[ccp4bb] short term PDRA post available

2017-06-02 Thread Jim Spencer
Dear all, I have a short term (~1 year) PDRA post available to work on structural and mechanistic studies of metalloenzymes involved in antibiotic resistance in bacteria. Details of the post, and how to apply, are at http://www.bristol.ac.uk/jobs/find/- search for post reference ACAD102676. The

[ccp4bb] PhD positions in protein design at University Bayreuth, Germany

2017-06-02 Thread Birte Höcker
PhD positions in biochemistry/structural biology/computational modeling available at the Biochemistry Department of the University Bayreuth/Germany we study sequence-structure-function relationships with the goal of rationally designing robust and functional proteins. On the one hand we

[ccp4bb] AW: [ccp4bb] help needed to interpret a SRF

2017-06-02 Thread Herman . Schreuder
Hi Vincent, To calculate the best possible (self)rotation function, you want to have as many as possible intramolecular vectors (within the search molecule) and as little as possible intramolecular vectors (between molecules in the crystal). These latter vectors are meaningless (noise) as long

[ccp4bb] Job Offer: Structural Biologist-Membrane Proteins, Vertex Pharmaceuticals UK

2017-06-02 Thread Christopher Browning
Structural Biologist-Membrane Proteins Structural Biology and Biophysics (UK) Abingdon, Oxon, UK Full-Time Job Description Summary: Vertex Pharmaceuticals (Europe) Ltd has an immediate opening for a talented membrane protein structural biologist in the Structural Biology and Biophysics

[ccp4bb] Research Scientist Positions at Vertex Pharmaceuticals UK site

2017-06-02 Thread Jay Bertrand
Dear All, Vertex Pharmaceuticals (Europe) Ltd has two open Research Scientist positions in the Structural Biology and Biophysics group at our UK site (Abingdon, Oxfordshire). One position is for a structural biologist with experience in Cryo-EM and/or membrane protein crystallography and the

[ccp4bb] tenure-track academic fellowships in structural molecular biology at the University of Leeds

2017-06-02 Thread Joe Cockburn
Hello everyone, Please see the job advert below regarding tenure-track academic fellowships in structural molecular biology at the University of Leeds. Cheers, Joe Dear All, A number of tenure-track academic fellowships in Structural Molecular Biology are now available at the University of