On 28 July 2010 16:54, Jan-Stefan Van der Walt
janstefan.vanderw...@gmail.com wrote:
Dear Matt,
In my experience, using ADVAN13 (NONMEM7) reduces the estimation time for
the transit compartment model. Also, you can use DOSTIM to capture the time
of doses specified using the ADDL data item
Dear Matt,
In my experience, using ADVAN13 (NONMEM7) reduces the estimation time for
the transit compartment model. Also, you can use DOSTIM to capture the time
of doses specified using the ADDL data item when using the analytical
solution published by Savic et al.
Regards from Uppsala,
Dear Matt,
We published a multiple-dose implementation of the transit model a little
while back which may be of help (although it uses the mathematical solution
from Savic et al 2007, and assumes the entire bioavailable dose has left the
absorption compartment before the next dose is given). I'm
