>Date: 20 May 2001 23:15:03 -0000 >To: List Member <[EMAIL PROTECTED]> >Reply-To: [EMAIL PROTECTED] >From: "Fuel and Fiber Company" <[EMAIL PROTECTED]> >Subject: Genencor Identifies Structure of a Novel Fungal Cellulose: >Findings to Lead to the Development of Enzymes for More Efficient I > >Genencor Identifies Structure of a Novel Fungal Cellulose: Findings >to Lead to the Development of Enzymes for More Efficient Industrial >Processes >Source: Source: Genencor International, Inc. / PRNewswire >05/09 > > >Genencor International, Inc. (Nasdaq: GCOR) announced today (April >30, 2001) the publication, in a peer-reviewed journal, of results >describing the structure of a commercially important fungal >cellulase, Cel12A (EG3). This work will enable Genencor to develop >improved novel cellulase enzymes designed to enhance the efficiency >of industrial processes including the production of detergents, >textiles, food, paper and fuel alternatives such as ethanol. > >The paper, published in the Journal of Molecular Biology, entitled >"The X-ray crystal structure of the Trichoderma reesei family 12 >endoglucanase 3 (Cel12A) at 1.9A," describes results from an >international collaboration between scientists at Genencor, and both >Uppsala University and the Swedish University of Agricultural >Sciences in Uppsala, Sweden. Using X-ray crystallography, the >scientists determined the specific structural features of the Cel12A >protein that provide important insight into the mechanism of action >of the protein. >"This publication further validates Genencor's in-depth expertise in >fungal biology, protein chemistry, and crystallography," commented >Michael Arbige Ph.D., Senior Vice President of Research and >Development. "Such core competencies are an integral part of our >i-biotech(TM) solution, which integrates our full suite of >technologies, facilitating the rapid development of more effective >and safer biologically engineered materials for the consumer, >industrial and health care markets." > >Cellulases are a commercially important class of enzymes found in >fungal and bacterial microorganisms that utilize plant matter as one >of their primary carbon sources. They are responsible for the >degradation of plant cell walls and provide a fast and effective >means of releasing important fermentable sugars from plant matter. >By understanding the precise locations of amino acids within the >protein, Genencor can incorporate this information into its >molecular evolution and design platform to accelerate the natural >evolutionary process and genetically engineer, and optimize, >biomaterials in more advantageous ways. Furthermore, the integration >of these data into Genencor's immunology platform allows assessment >and elimination of potential allergenic risk from newly created >biomaterials. Novel enzymes derived from these processes will, for >example, be evaluated to enhance the technology for ethanol fuel >production from cellulose biomass. > >About Genencor >Genencor International is a diversified biotechnology company that >develops and delivers innovative products into the health care, >agriculture, and industrial and consumer markets. Using an >integrated set of technology platforms, Genencor's products deliver >innovative and sustainable solutions to many of the problems of >everyday life. >Genencor was established in 1982 as a joint venture between >Genentech Inc. and Corning Incorporated. Since its founding, >Genencor has grown to become a leading biotechnology company, with >over $315 million in annual revenues, more than 250 biotechnology >products in commerce, and over 3,400 owned and licensed patents and >applications. Genencor, with more than 1,500 employees worldwide, >has principal offices in Palo Alto, California; Rochester, New York; >and Leiden, the Netherlands. > >Except for the historical information contained herein, the matters >discussed in this press release may contain forward-looking >statements which involve risks and uncertainties, including >significant fluctuations in product performance depending on factors >such as a dependence on the efforts of third parties, a new and >uncertain technology employed by Genencor and its uncertain >application to new business ventures, dependence on intellectual >property rights, the competitive nature of Genencor's industry and >risks of obsolescence of certain technology. Actual results may >differ materially from those projected. Forward-looking statements >represent the judgment of Genencor as of the date of this release. >Genencor disclaims, however, any intent or obligation to update any >forward-looking statements. >(C) 2001 PR Newswire. All rights reserved. > >_______________________________________________________________________ >Powered by List Builder >To unsubscribe follow the link: >http://lb.bcentral.com/ex/manage/subscriberprefs?customerid=360&subid >=0A665AD4E0AC5E6B&msgnum=53
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