Unless you have the spare cash, time and resources then the
whole argument is moot, and you must find another way of achieving the goals
within your means.  You can negate most of the above by taking a leaf out the
Wright brothers methodology… take a leap of faith (in yourself) and just build
the damn thing, make it work… prove it works.


Every now and again I like to take a break from teaching/
designing my AGI’s and consider human frailties, and check if my design can
simulate the symptoms, and/ or give any insights into the prognosis/ diagnosis
or cure.


I have a list, roughly ordered by complexity and today it’s
the turn of terminal or paradoxical lucidity (PL).  Paradoxical Lucidity is one 
of natures
cruellest tricks, approx 75% of patients with long term dementia will fully/
partially become conscious/ lucid shortly before they die.  It’s a very complex 
diagnosis that ties into
many other conditions and I’m greatly over simplifying the topic for the
purpose of explanation.


 
https://www.sciencedirect.com/science/article/pii/S1552526019300950


Considering the phenomena in its simplest terms obviously
begs the question of how this can happen/ function. It seems intuitive that for
normal (ish) function to return the symptoms of dementia cannot be caused by
permanent damage/ change, or that something like a build up of amyloid plaque
is ultimately responsible, but something is impeding consciousness, so what
could it be.


Keep in mind I have already done this for a myriad of
conditions and phenomena, so I have insight into how my model behaves/
functions.  I’ve replicated optical/
audio illusions, pareidolia, schizophrenia, hallucinations, hypnotism,
meditation (states of mind), epilepsy, anaesthesia, NDE, and many more, all
with in the same model.


Firstly I read as much empirical information about the subject
as possible. Then formulate a theory of how those symptoms could arise and
manifest within my model. I then alter the models balances and test, repeat 
until
I get the desired results, making notes all the way.


Within my model memory consolidation and consciousness are
extremely sensitive to the base frequencies of the Global Thought Pattern (GTP).
The high dimensional facets of memories are encoded/ indexed by the state of
the GTP performing the task at hand, consciousness manifests from the harmonics
within the GTP.


 
https://www.youtube.com/watch?v=dJmdWfDTgLQ


This shows a small section (1.2mm², 0.01%, 10K neurons, 200K
synapse) of cerebral cortex from my model, I use it for testing hypotheses and
it encompasses all the functionality of the full model. It’s learned 40K memory
engram's segmented into 80 pattern concepts along with a regular base GTP
rhythm. The graph (lower left) function is equivalent to real-time colour coded
Golgi staining, and shows the confidence the model has in recognising the
current pattern, shown by the scrolling bar. Notice the actual pattern stream/
matrix on the upper right along with the injected regular GTP rhythm just
below. On the first pass it shows a very high confidence in recognising the all
patterns, both the episodic sequence memories and the memories regarding the
pattern structure are being recalled/ accessed.  On the second pass I change 
the base frequency of just the GTP, notice
how the memory retrieval/ recognition becomes sporadic. On the third pass I cut
the GTP and the confidence totally drops even though the 80 patterns are still
being injected. I then re-establish the GTP and normal operation resumes. This
shows how reliant/ sensitive the system is to the state of the underlying base 
GTP
frequencies.


The slow onset of dementia hints at the second pass, it’s
not like the global GTP disruption caused by anaesthetic, so I don’t think it’s
an imbalance in the neurotransmitter levels/ medium.  It must also be affecting 
the well
established networks with diminished plasticity; otherwise the brain would just
adapt to the disruptions and wouldn’t then be able to exhibit the PL phenomena.


So one cause of dementia could be an alteration of the base
frequencies within the GTP, and the PL phenomena could mean that whatever is
causing the phase change is related to a condition that rises or reduces/
diminishes just before death. Allowing the GTP to phase back through its normal
frequency domain and thus allowing consciousness to temporarily return.  My 
current main candidate is intracranial
pressure, as altering the shape of the connectome can also have adverse effects
on the phase of the GTP, further pondering is required.


My point being that… although there is no empirical data on
how the human brain functions it is still possible to gain insights and build a
working model through experimentation and cross reference, and although this is
a low resolution insight into the functioning of the brain it hints that so far
my schema is correct.


Indeed, IMO this is the only way to do it, you have to work
the problems. Applying/ finding empirical scientific proof of every required
step/ concept would make the project impossible, especially to a lone
researcher with limited resources.


 
:)
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