Hi, Over the last 15 years, every 3 years or so we get yet another paper that takes us all towards the centralisation of brain signalling on the EM fields. Not _away_ from such an idea. _Towards_ that idea.
This is merely the latest in that long vector towards EM fields as central to brain operation. ============================================ Moore, J.J., Ravassard, P.M., Ho, D., Acharya, L., Kees, A.L., Vuong, C., and Mehta, M.R. (2017). Dynamics of cortical dendritic membrane potential and spikes in freely behaving rats. Science. earlier Arxiv version http://biorxiv.org/content/early/2016/12/28/096941 See http://science.sciencemag.org/content/early/2017/03/08/science.aaj1497 and commentary "Why our brains may be 100 times more powerful than believed" here: http://newatlas.com/brains-more-powerful/48357/ ==================================================== Guess what?: 'Dendritic Action Potentials' (DAP) must now become a thing. All your simulation packages? Just got old. All your neuromorphic chips? Has-beens. SOMATIC AP is 60 years old. DENDRITIC AP now comes home. Neocortical sub- and suprathreshold dendritic membrane potential (DMP) breaking out into localised firing within the dendrite structure. Dendrite firing has been observed for a long time, but this is the first time anyone has seriously accessed its origins and correlated it with behaviour. Collectively the DMP are very strong (as represented by voltage measured in tissue: Higher than somatic action potentials!) This is because neural tissue is 90% dendritic and there are collosal numbers of post-synaptic densities (synapses). The implication ... you guessed it .... the brain is not a computer (analog or digital) but a system of interacting fields who's long-distance outward signs ... the tip of the iceberg ... are soma-related action potentials. I reckon it's at least 3 orders of magnitude more complex, not just two....because it's totally spatialised and interacting at distance at near the speed of light. It is physically impossible for any signals to operate chemically (ion-channel ion transport leading to extracellular ion motion = currents) on the fast timescales found to actually operate in the dendrites. Ions can barely move a nanometer on those timescales. There are NO currents at all! No current can possibly be the origin of collective signalling of this kind. The fields? No problem. Action at a distance. Speed of light. Remotely-activated modulation of remote transmembrane fields (in this case the post-synaptic density of ion channels, advancing and retarding signal events). Easy. Plain old classical physics of the Lorentz force. Field systems exactly of the kind I did in my PHD thesis. And exactly the same thing in my chip design ... what I am experimentally working on already ... my proposed system does this naturally. This is because I have no neurons in my design. I merely have loci of signalling that does the same thing dendrites/soma/axons do. This seems like a big deal to me. Is that 'ol penny gonna drop this time? How much evidence can a system ignore before it goes bang and shifts. (Reminds me of a certain political context ... let's not go there) :-) Back to testing. cheers colin ------------------------------------------- AGI Archives: https://www.listbox.com/member/archive/303/=now RSS Feed: https://www.listbox.com/member/archive/rss/303/21088071-f452e424 Modify Your Subscription: https://www.listbox.com/member/?member_id=21088071&id_secret=21088071-58d57657 Powered by Listbox: http://www.listbox.com
