BTW check out supplementary video 1 to see the DAP firings correlated with
extracellular LFP! We've been missing these little suckers all along!

http://science.sciencemag.org/content/suppl/2017/03/08/science.aaj1497.DC1


Q. "What is it like to BE a huge mass of 10^14 DAP all spatially arranged?"

Maybe it's like .... consciousness?

cheers
colin


On Tue, Mar 14, 2017 at 1:11 PM, Colin Hales <[email protected]> wrote:

> Hi,
>
> Over the last 15 years, every 3 years or so we get yet another paper that
> takes us all towards the centralisation of brain signalling on the EM
> fields. Not _away_ from such an idea. _Towards_ that idea.
>
> This is merely the latest in that long vector towards EM fields as central
> to brain operation.
>
> ============================================
> Moore, J.J., Ravassard, P.M., Ho, D., Acharya, L., Kees, A.L., Vuong, C.,
> and Mehta, M.R. (2017). Dynamics of cortical dendritic membrane potential
> and spikes in freely behaving rats. Science.
> earlier Arxiv version
> http://biorxiv.org/content/early/2016/12/28/096941
>
> See http://science.sciencemag.org/content/early/2017/03/08/science.aaj1497
> and commentary
> "Why our brains may be 100 times more powerful than believed"
> here: http://newatlas.com/brains-more-powerful/48357/
> ====================================================
>
> Guess what?: 'Dendritic Action Potentials' (DAP) must now become a thing.
> All your simulation packages? Just got old. All your neuromorphic chips?
> Has-beens.
>
> SOMATIC AP is 60 years old.
> DENDRITIC AP now comes home.
>
> Neocortical sub- and suprathreshold dendritic membrane potential (DMP)
> breaking out into localised firing within the dendrite structure. Dendrite
> firing has been observed for a long time, but this is the first time anyone
> has seriously accessed its origins and correlated it with behaviour.
> Collectively the DMP are very strong (as represented by voltage measured in
> tissue: Higher than somatic action potentials!) This is because neural
> tissue is 90% dendritic and there are collosal numbers of post-synaptic
> densities (synapses).
>
> The implication ... you guessed it .... the brain is not a computer
> (analog or digital) but a system of interacting fields who's long-distance
> outward signs ... the tip of the iceberg ... are soma-related action
> potentials. I reckon it's at least 3 orders of magnitude more complex, not
> just two....because it's totally spatialised and interacting at distance at
> near the speed of light.
>
> It is physically impossible for any signals to operate chemically
> (ion-channel ion transport leading to extracellular ion motion = currents)
> on the fast timescales found to actually operate in the dendrites. Ions can
> barely move a nanometer on those timescales. There are NO currents at all!
> No current can possibly be the origin of collective signalling of this kind.
>
> The fields? No problem. Action at a distance. Speed of light.
> Remotely-activated modulation of remote transmembrane fields (in this case
> the post-synaptic density of ion channels, advancing and retarding signal
> events). Easy. Plain  old classical physics of the Lorentz force. Field
> systems exactly of the kind I did in my PHD thesis.
>
> And exactly the same thing in my chip design ... what I am experimentally
> working on already ... my proposed system does this naturally. This is
> because I have no neurons in my design. I merely have loci of signalling
> that does the same thing dendrites/soma/axons do.
>
> This seems like a big deal to me. Is that 'ol penny gonna drop this time?
> How much evidence can a system ignore before it goes bang and shifts.
> (Reminds me of a certain political context ... let's not go there) :-)
>
> Back to testing.
>
> cheers
>
> colin
>
>



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