Hello,

I am currently principal investigator on a major NIH grant
that aims to develop software for test of hypothesis
using alternate hypothesis specified by the user and that
differ from the omnibus "spatial independence";
we called them "spatial neutral models".
For example, you can test for clusters of cancer rates
"above and beyond" a regional background in exposure.
The p-values are computed using randomization and I applied
geostatistical simulation to generate multiple realizations
that are then used to derive the empirical distribution of
the test statistic.

I presented an example during the last GeoEnv conference
and I put a PDF copy of the paper, which is in press for
the moment, on my website.

Cheers,

Pierre

<><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><>

Dr. Pierre Goovaerts
President of PGeostat, LLC
Chief Scientist with Biomedware Inc.
710 Ridgemont Lane
Ann Arbor, Michigan, 48103-1535, U.S.A.

E-mail:  [EMAIL PROTECTED]
Phone:   (734) 668-9900
Fax:     (734) 668-7788
http://alumni.engin.umich.edu/~goovaert/

<><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><>

On Sun, 5 Dec 2004, Colin Daly wrote:

>
>
> Hi
>
> Sorry to repeat myself - but the samples are not independent.  Independance 
> is a fundamental assumption of these types of tests - and you cannot 
> interpret the tests if this assumption is violated.  In the situation where 
> spatial correlation exists, the true standard error is nothing like as small 
> as the (s/sqrt(n)) that Chaosheng discusses - because the sqrt(n) depends on 
> independence.
>
> Again, as I said before, if the data has any type of trend in it, then it is 
> completely meaningless to try and use these tests - and with no trend but 
> some 'ordinary' correlation, you must find a means of taking the data 
> redundancy into account or risk get hopelessly pessimistic results (in the 
> sense of rejecting the null hypothesis of equal means far too often)
>
> Consider a trivial example. A one dimensional random function which takes 
> constant values over intervals of lenght one - so, it takes the value a_0 in 
> the interval [0,1[  then the value a_1 in the interval [1,2[ and so on (let 
> us suppose that each a_n term is drawn at random from a gaussian distribution 
> with the same mean and variance for example).  Next suppose you are given 
> samples on the interval [0,2]. You spot that there seems to be a jump between 
> [0,1[ and [1,2[  - so you test for the difference in the means. If you apply 
> an f test you will easily find that the mean differs (and more convincingly 
> the more samples you have drawn!). However by construction of the random 
> function,  the mean is not different.  We have been lulled into the false 
> conclusion of differing means by assuming that all our data are independent.
>
> Regards
>
> Colin Daly
>
>
> -----Original Message-----
> From: Chaosheng Zhang [mailto:[EMAIL PROTECTED]
> Sent: Sun 12/5/2004 11:42 AM
> To:   [EMAIL PROTECTED]
> Cc:   Colin Badenhorst; Isobel Clark; Donald E. Myers
> Subject:      Re: [ai-geostats] F and T-test for samples drawn from the same p
> Dear all,
>
>
>
> I'm wondering if sample size (number of samples, n) is playing a role here.
>
>
>
> Since Colin is using Excel to analyse several thousand samples, I have 
> checked the functions of t-tests in Excel. In the Data Analysis Tools help, a 
> function is provided for "t-Test: Two-Sample Assuming Unequal Variances 
> analysis". This function is the same as those from many text books (There are 
> other forms of the function). Unfortunately, I cannot find the function for 
> "assuming equal variances" in Excel, but I assume they are similar, and 
> should be the same as those from some text books.
>
>
>
> From the function, you can find that when the sample size is large you always 
> get a large t value. When sample size is large enough, even slight 
> differences between the mean values of two data sets (x bar and y bar) can be 
> detected, and this will result in rejection of the null hypothesis. This is 
> in fact quite reasonable. When the sample size is large, you are confident 
> with the mean values (Central Limit Theorem), with a very small stand error 
> (s/(sqrt(n)). Therefore, you are confident to detect the differences between 
> the two data sets. Even though there is only a slight difference, you can 
> still say, yes, they are "significantly" different.
>
>
>
> If you still remember some time ago, we had a discussion on large sample size 
> problem for tests for normality. When the sample size is large enough, the 
> result can always be expected (for real data sets), that is, rejection of the 
> null hypothesis.
>
>
>
> Cheers,
>
>
>
> Chaosheng
>
> --------------------------------------------------------------------------
>
> Dr. Chaosheng Zhang
>
> Lecturer in GIS
>
> Department of Geography
>
> National University of Ireland, Galway
>
> IRELAND
>
> Tel: +353-91-524411 x 2375
>
> Direct Tel: +353-91-49 2375
>
> Fax: +353-91-525700
>
> E-mail: [EMAIL PROTECTED]
>
> Web 1: www.nuigalway.ie/geography/zhang.html
>
> Web 2: www.nuigalway.ie/geography/gis/index.htm
>
> ----------------------------------------------------------------------------
>
>
>
>
>
> ----- Original Message -----
>
> From: "Isobel Clark" <[EMAIL PROTECTED]>
>
> To: "Donald E. Myers" <[EMAIL PROTECTED]>
>
> Cc: "Colin Badenhorst" <[EMAIL PROTECTED]>; <[EMAIL PROTECTED]>
>
> Sent: Saturday, December 04, 2004 11:49 AM
>
> Subject: [ai-geostats] F and T-test for samples drawn from the same p
>
>
>
>
>
> > Don
>
> >
>
> > Thank you for the extended clarification of F and t
>
> > hypothesis test. For those unfamiliar with the
>
> > concept, it is worth noting that the F test for
>
> > multiple means may be more familiar under the title
>
> > "Analysis of variance".
>
> >
>
> > My own brief answer was in the context of Colin's
>
> > question, where it was quite clear that he was talking
>
> > aboutthe simplest F variance-ratio and t comparison of
>
> > means test.
>
> >
>
> > Isobel
>
> >
>
> >
>
>
>
>
>
> --------------------------------------------------------------------------------
>
>
>
>
>
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> > Signoff ai-geostats
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> >
>
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