I don't know anything specific, but you could try using 'Gibbs
sampling' algorithms to automatically discover the motif in the
sequence sets?



On 13 May 2010 21:02, Che, Anney (NIH/NCI) [E] <[email protected]> wrote:
>
> Hi everyone,
>
> I have questions regarding on how to create a transcription binding sites 
> profile.
>
> Since I have the sequences of the areas that bind to the gene from Chip-ChIp 
> , I can align all the sequences then with the alignment that created to 
> generate a profile.
>
> Since this is high-throughput, does any one know any tool that can align 
> short sequences programmatically and then output an alignment file?
>
> Also a program that generates an alignment profile from an alignment.
>
>
> Thanks,
>
> Anney
>
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