Thanks Matthew,

To produce a pair-wise alignment from two un-aligned sequences and introduce gaps I have used the sample at "BioJava In Anger" and it runs successfully.

Now I need an alignment of two sequences where one of them already have gaps before I align.

I mean that the DP class don´t accept GappedSequence, it´s right?

[]s
Guedes

Matthew Pocock escreveu:
If I understand you correctly, one of the two sequences you are aligning contains a gap before you align them? Or do you want to produce a pair-wise alignment from two un-aligned sequences and introduce gaps?

If it is the former, you want a state that emits a gap in one sequence and a symbol in the other, and also advances {1,1}. I think that is easy enough to set up, but can't remember the exact code. If the worst comes to the worst, you can construct the distribution over {gap,Protein} using the classes in .dist and then set up a SimpleState, providing the advance and alphabet in the constructor.

Matthew
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:: Dickson S. Guedes (guedes at unisul dot br)
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