On Thursday 19 February 2009 22:48:45 Ashika Umanga Umagiliya wrote:

> My problem is can I use the same Quality files ,with  the modified
> callbases ?

Edit the quality data in parallel with the chromatogram.  I would assume that 
the editor is relatively sure of their edits, so I would give them a high 
confidence level when I generate the trace fasta and quality file.
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