--- Jon Gabriel <[EMAIL PROTECTED]> wrote:
> >Ronn! Blankenship <[EMAIL PROTECTED]> wrote:
[I wrote:]
<snip> 
> >> To open another COW, what do we do about
> conditions which have genetic causes?  
> >
> >Shades of _Gattaca_...
> 
> Or of Heart of the Comet.  I'm sure the Percells
> would agree that
> eliminating disease didn't solve their problems.
> 
> >> If a young person tests positive for
> >> Huntingdon's disease, do we 
> >> sterilize that person before puberty so they
won't
> >> pass along the bad genes 
> >> and then offer them euthanasia when the symptoms
> >> start in their 40s?  How 
> >> about children with hemophilia, cystic fibrosis,
> or Down's syndrome?  (And 
> >> how about their parents?)  Mandatory prenatal
> >> genetic screening followed by 
> >> mandatory abortion if the fetus is not "perfect"?
> >> And if so, where do we 
> >> draw the line on what is considered a genetic 
> >> "disease"?  Homosexuality?  Below-normal
> >> intelligence?  Above-normal intelligence?
> >
> >Now you're talking social engineering (if I
> understand
> >the term correctly), which is quite beyond 'trying
> to reduce medical costs.' 
> 
> Re: Social engineering issues
> 
> These are all issues which will no doubt be raised
> and debated to death
> in forums way before they reach the point where we
> will be able to do anything about them.  
> 
> Cystic Fibrosis, Huntingdon's, Tay-Sachs, Hemophilia
> and Down's Syndrome
> are considered severe diseases by the medical
> community.  Since tests
> currently exist to detect the possibility of passing
> on these defects to
> one's offspring for all of the above, we can
> probably assume that if
> cures become available (through genetic
> manipulation) they will be offered to the masses. 

Well, single-gene defects like "bubble boy disease"
(severe combined immune deficiency) are under
experimental 'attack' even as we speak (that protocol
was temporarily halted when one of the ~9 boys
developed leukemia, but oversight panel(s) have since
reinstated the trial) - so the time for discussion is
now.  A chromosomal mutation like Down's (trisomy 21),
on the other hand, doesn't appear amenable (to me) to
gene therapy, although it is discoverable if chorionic
villi sampling or amniocentesis are done; I know what
my choice would be, but I would not impose that on
another.  <serious>
 
> I think the key word here is "offered".  Most
>...theories on this subject, IMO, seem paranoid...  
> like our culture will force cures...[on] people...
> If a _communicable_ disease threatens large
> population groups then we can
> logically expect to see vaccines and cures become
> mandatory by law.

As is the case with school vaccines (although parents
can, in many states IIRC, opt out b/c of religious
beliefs), and treatment for tuberculosis is also
mandated (at least in the states I've worked in).

> ...But, when a disease affects specific groups and
is
> non-communicable except from parent to child through
> genetics, then IMO
> such mandatory laws are highly unlikely to be
> enacted.  

Probably not, although courts do become involved in
the treatment of minors.  But what parent would not
want a cure for such devastating diseases?  Who would
not want their child to participate freely in
academics and sports, live to 'old' adulthood, be able
to have healthy children? 

<grimace> Of course there are parents who refuse
treatment even today for quite treatable conditions
(diabetes, meningitis, appendicitis to name a few -
see
http://www.rickross.com/reference/firstborn/firstborn16.html?FACTNet).

While I respect the right of an adult 'consciencious
objecter' to refuse life-saving treatment, I have a
much harder time saying, "Well, Darwin at work!" when
a child is suffering (frex, dying of a ruptured
appendix is *quite* painful, and an otherwise healthy
kid might hang on for days).  If the condition is not
painful, or the child is unable to feel anything
(comatose, frex), then - <sigh> I'd have to take it on
a case-by-case basis.  I certainly do not advocate
futile treatment, for children or adults.

Ah - sorry for the digression.
 
> AFAIK, Homosexuality and Low/High IQ's are not
> recognized in the medical community as diseases.

Not as such.  They may cause real problems for the
individual, but so can being short, or red-headed.
[Kids will find _something_ to rag on each other about
- which is why my mother harped to me: "How would YOU
feel if somebody laughed at you, because you have
moles?"  Fear and guilt, indeed... :) ]

> Mental retardation is, but I'm not sure the
> causes are usually genetic.  Isn't the brain damage
> most frequently
> caused by oxygen deprivation as a result of
> drug/alcohol use during
> pregnancy or complications during birth?

I think it's more multi-causal than that (although
hypoxia is absolutely a potential brain-hammer; I say
potential because _all_ vaginal births involve a
certain amount of hypoxia, which we all have obviously
survived).  I'll try to look into this in the next
couple of weeks [still have a looong post to finish
for Dan! :) ]  And there is NO safe level of alcohol
in the first trimester AFAIK; tobacco and street drugs
are definitely harmful, but not through hypoxic
mechanisms IIRC.
<snippage> 
>  
> >In the not-to-distant future, we will be able to
> >prevent or treat many if not all of the diseases
> >mentioned.  While I applaud elimination of needless
> >suffering, I do not like the idea of
> >"custom-designing" a child to be a blue-eyed,
> >red-headed 6' 7"  basketball player who paints and
> >likes pythons. Will we tinker with our genes? 
> >Probably.  
> 
> All it will take is one Percell-style mistake for
> any such project to
> fold, permanently.  I doubt that will prevent
> mankind from making an attempt, though.
> 
> Jon
> GSV How *much* does he like pythons?
> "OK, you can love your pets, but not LOOOVE your
> pets!"
> ~Jeaneane Garafolo / The Truth About Cats & Dogs

<LOL>
Either my funny bone is awfully sensitive today, or
the list is especially witty.  I thought that movie
was hysterical, BTW!

Mayhap There Is A Touch Of Sleep Deprivation Involved?
Maru


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