Hi Donna,
>> 1. create a target surface from the SPM-normalized T1s of each of the
>> participants: this is not a very nice representation, but it shows
>> very clear landmarks (with the possible exception of the ventral
>> medial wall);
> So far, so good. What software will you use to generate the surfaces?
My description was incomplete: I meant average the participant-specific
SPM-normalized T1s to create a group-average T1. Then create a target
surface by segmenting this group T1 with Caret. This surface will
obviously look bad. However, it still has each of the default landmarks
very clear. This target surface will be improved at point 3.
>> 2. project the surfaces of the participants (derived from
>> SPM-normalized T1s) onto this target surface;
> This isn't really clear. As best I can discern, you mean register your
> subjects to the PALS-B12 target atlas, at which time your various coord
> files, including fiducial/midthickness coord files, will get resampled
> onto the PALS-B12 73730 standard mesh.
See above.
>> 3. create a new improved target surface by averaging those coming out
>> from 2. (eventually include the additional temporal landmarks at this
>> point and not at 1.).
> Why? What is your motivation for creating a customized target, instead
> of using PALS-B12? What is different about your subjects?
My thought is that by using a target surface that actually comes out
from my subjects the quality of the functional-to-surface mapping will
be improved, especially if I do the points 4-6. below:
>> 4. project the surfaces of the participants used at 2. on the new target;
>> 5. average surfaces coming out at 4;
>> 6. project my functionals (group results) onto the average surface
>> from 5.
Please correct me if I'm wrong. Thank you again,
Bruno
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