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Dear memebers, I recently solved one complex structure: cyaa with c-terminal CaM. Now I am trying to build the N-terminal CaM in through the modeling method. CaM contants N- and C-terminal through a flexible helix. it have different conformations through NMR result. if N-termianl is fixed, C-terminal have the rotating conformation. I am looking for a program or some methods to do the modeling and find one reasonable conformation to N-terminal. If someone has the similar experience, would you like to share your experience with me? Any suggestions and comments are welcomed. Guo, Qing University of Chicago ------------------------------------------------- This email is intended only for the use of the individual or entity to which it is addressed and may contain information that is privileged and confidential. If the reader of this email message is not the intended recipient, you are hereby notified that any dissemination, distribution, or copying of this communication is prohibited. If you have received this email in error, please notify the sender and destroy/delete all copies of the transmittal. Thank you. -------------------------------------------------
