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Bernhard Rupp wrote:

I run refmac 5.2.0019 on a structure with sequence gaps.
Refmac finds those and enters the proper gap links
LINK             ASN A  34                     SER A  37                gap
LINK             LEU A  67                     GLY A  69                gap
LINK             THR A 125                     SER A 127                gap
LINK             SER A 130                     ALA A 132                gap
LINK             GLY A 189                     LYS A 192                gap
LINK             LYS A 208                     LEU A 213                gap
LINK             SER A 221                     GLY A 223                gap
LINK             ALA A 225                     GLN A 227                gap

but does not seem to use them, the link distances are all over the place.


Seems to me that is exactly the behavior you would expect with a "gap"
link. If you want the the residues connected, shouldn't there be a
peptide link? I assume gap link (gap patch?) means deleting
the peptide and perhaps adding an OXT to the new C-term.

If you delete a few residues because they are not clear in
the density, in general the last thing you want is for the residues
on either side of the gap to be linked- the peptide bond yanks both
chains out of the density and destroys your structure.


Ed

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