Dear Jacob, We have been working on this for an year or so. We have a paper partially in the review process. Unfortunately, the referees were not very excited about the idea. However, we are developing some automation to speed up the time consuming process of placing the drops on the loops.
This method seems to have some advantges and some issues in using the known crystallization conditions. This could also give trouble with solutions containing volatile compounds. Kind regards, Mathews -----Original Message----- From: CCP4 bulletin board [mailto:[EMAIL PROTECTED] On Behalf Of Jacob Keller Sent: Tuesday, June 03, 2008 1:14 PM To: [email protected] Subject: [ccp4bb] Crystals grown directly on loop? Dear crystallographers, Has anyone ever tried to grow crystals directly on some kind of mountable support, such as some kind of loop or film, which could be frozen directly? I understand that there are some microfluidic plates through which the crystals can be diffraction-screened, but what about for more conventional, known crystallization conditions? It seems that this would be a spectacular way to decrease damages/stresses caused by handling... Jacob Keller ******************************************* Jacob Pearson Keller Northwestern University Medical Scientist Training Program Dallos Laboratory F. Searle 1-240 2240 Campus Drive Evanston IL 60208 lab: 847.491.2438 cel: 773.608.9185 email: [EMAIL PROTECTED] *******************************************
