Dear Jacob and Mathew,
one night at the pub a few months ago a colleague and I
had been thinking along similar lines but we were rather envisaging
microcapillaries feeding the mother liquor components into the loop at
controlled rates from the stem ... expensive hi-tech loops to be sure
but maybe not so in a few years should technology stay with us for
longer. Time will tell.
Good luck with your efforts!
Pietro
> Dear Jacob,
>
> We have been working on this for an year or so. We have a paper partially in
> the review process. Unfortunately, the referees were not very excited about
> the idea. However, we are developing some automation to speed up the time
> consuming process of placing the drops on the loops.
>
> This method seems to have some advantges and some issues in using the known
> crystallization conditions. This could also give trouble with solutions
> containing volatile compounds.
>
> Kind regards,
> Mathews
>
>
> -----Original Message-----
> From: CCP4 bulletin board [mailto:[EMAIL PROTECTED] On Behalf Of Jacob Keller
> Sent: Tuesday, June 03, 2008 1:14 PM
> To: [email protected]
> Subject: [ccp4bb] Crystals grown directly on loop?
>
> Dear crystallographers,
>
> Has anyone ever tried to grow crystals directly on some kind of mountable
> support, such as some kind of loop or film, which could be frozen directly?
> I understand that there are some microfluidic plates through which the
> crystals can be diffraction-screened, but what about for more conventional,
> known crystallization conditions? It seems that this would be a spectacular
> way to decrease damages/stresses caused by handling...
>
> Jacob Keller
>
> *******************************************
> Jacob Pearson Keller
> Northwestern University
> Medical Scientist Training Program
> Dallos Laboratory
> F. Searle 1-240
> 2240 Campus Drive
> Evanston IL 60208
> lab: 847.491.2438
> cel: 773.608.9185
> email: [EMAIL PROTECTED]
> *******************************************
--
Pietro Roversi
Sir William Dunn School of Pathology, Oxford University
South Parks Road, Oxford OX1 3RE, England UK
Tel. 0044-1865-275385
