There are a number of examples of nuclear receptor heterodimers, where crystallization of the individual partner, such as PPAR or LXR, crystallizes as a homodimer, even though these species do not exist in solution. There are also many examples of dimers showing one molecule per asymmetric unit, but the physiological dimer is apparent in the crystal packing.
Kendall Nettles On 12/11/08 11:09 AM, "Santarsiero, Bernard D." <[EMAIL PROTECTED]> wrote: > In parallel with the discussion around this off-CCP4-topic, are they any > good examples of the opposite case, where the protein is a monomer in > solution (as evident from light scattering, MW determination through > centrifugation, EPR, etc.) but crystallizes as a dimer or higher multimer? > > Bernie Santarsiero
