Santarsiero, Bernard D. wrote:
In parallel with the discussion around this off-CCP4-topic, are they any
good examples of the opposite case, where the protein is a monomer in
solution (as evident from light scattering, MW determination through
centrifugation, EPR, etc.) but crystallizes as a dimer or higher multimer?
Bernie Santarsiero
Sometimes proteins are (mostly) monomers in solution and become
domain-swapped trimers in the crystal.
Zegers et all, PNAS 1999 Feb 2;96(3):818-22
kind regards,
Klaas
