If you have 1.1A data and your structure is not too large, ab initio direct methods (e.g. with SHELXD) will probably solve the structure. I would be happy to advise if you wish to try this.
George Prof. George M. Sheldrick FRS Dept. Structural Chemistry, University of Goettingen, Tammannstr. 4, D37077 Goettingen, Germany Tel. +49-551-39-3021 or -3068 Fax. +49-551-39-22582 On Fri, 19 Jun 2009, Sickmier, Allen wrote: > I am trying to do molecular replacement on a small peptide (less than 40 AA) > and have not had any success using phaser. Are there any tricks or better > programs for really small peptides? > The data is great 1.1 A, ~35% solvent, and two molecules in the ASU. I have > tried all the standard stuff, changing resolution cut off etc. I may move > to sulfur phasing at this resolution but I would like to get the MR to work. > > > Allen > > > > >
