You can try including some salt to the reservoir after mixing protein and well solution.

Joe


rui wrote:
Dear All,

I have a peri domain protein that is stable in high salt concentration(500 mM), if I dialysis to a lower salt buffer and then concentrate, it'll preticipate out. If I need to crystallize it, can I use the high salt buffer? Is there any optimization kits that could help to increase the solubility? Thanks.

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