Dear Zq Deng,
I've had success with the dilution method as described
by Dunlop and Hazes: http://scripts.iucr.org/cgi-bin/paper?en5016
For me it worked for a couple of projects, and gives you a bit more to
permutate than just varying the protein:mother liquor ratios, as Thomas
Edwards helpfully suggested.
Good luck,
Mark
On 6 May 2010 09:03, zq deng <[email protected]> wrote:
> hello,everybody . due to excess nucleation,I often get many tiny crystals
> instead of few,large crystals.i wana optimize the condition, does anyone
> have adivce about this?
>
> Best regards.
>
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Skype: markabrooks