It seems to me that spherical forms of Wilson plots could be used to determine how many bonds of what nature were oriented in which direction, and this may have been what Bricogne's micro molecular replacement technique was capitalizing on? For example, one might be able to orient a straight DNA molecule by finding the direction at which the ~3.2-3.5 Ang bin signal was greatest. But I guess this is probably implicit in molecular replacement anyway...
JPK On Wed, May 9, 2012 at 2:08 PM, Nat Echols <[email protected]>wrote: > On Wed, May 9, 2012 at 11:58 AM, Garib N Murshudov > <[email protected]> wrote: > > As far as I know there are several bumps: around 3.5-4 (there are some at > > low resolution related with molecular shapes also) - secondary > structures, > > ~2.2 related with angles and around 1.2 related with covalent bonds. For > > DNA/RNA there is one more bump around 1.6-1.7 ( I thought that is > because of > > Phosphor bonds). They are visible with normalised data better. > > It has been pointed out to me that my example cut off the data at too > low a resolution to see the peak for covalent bonds. Here is a > different version that shows a distinctive peak around 1.15A. > > -Nat > -- ******************************************* Jacob Pearson Keller Northwestern University Medical Scientist Training Program email: [email protected] *******************************************
