Nothing prescient about that. The MAD concept was first proposed by
Herzberg and Lau in 1967, much before sycnhrotrons were used for protein
crystallography.
Herzenberg, A. & Lau, H. S. M. (1967) Acta. Crystallogr. 22, 24-28.
http://scripts.iucr.org/cgi-bin/paper?S0365110X67000040
The PNAS paper even refers to this article.
Ganesh
Le 13/03/13 16:46, Jacob Keller a écrit :
Did anyone see this prescient line in the PNAS paper? Seems that the
MAD concept was suggested way back then...
JPK
"While the enhancement of anomalous scattering
has not yet been examined in detail, it is in principle
possible to use data collected at three wavelengths (15) to
completely solve the phase problem. The synchrotron source
is uniquely suited for these applications."